Facilitated osteogenesis of magnesium implant by coating of strontium incorporated calcium phosphate.

IF 1.6 4区医学 Q4 BIOPHYSICS

Biointerphases Pub Date : 2023-05-01 DOI:10.1116/6.0002598

Jung-Eun Park, Yong-Seok Jang, Jae-Min Seo, Min-Ho Lee

引用次数: 0

Abstract

This study investigated the corrosion resistance and biocompatibility of magnesium coated with strontium-doped calcium phosphate (Sr-CaP) for dental and orthopedic applications. Sr-CaP was coated on biodegradable magnesium using a chemical dipping method. Magnesium coated with Sr-CaP exhibited better corrosion resistance than pure magnesium. Sr-CaP-coated magnesium showed excellent cell proliferation and differentiation. Additionally, new bone formation was confirmed in vivo. Therefore, Sr-CaP-coated magnesium with reduced degradation and improved biocompatibility can be used for orthopedic and dental implant applications.

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磷酸钙锶包覆促进镁种植体成骨。

本研究研究了镁包覆锶掺杂磷酸钙(Sr-CaP)的耐腐蚀性和生物相容性，用于牙科和骨科应用。采用化学浸渍法将Sr-CaP包覆在可生物降解的镁上。包覆Sr-CaP的镁具有比纯镁更好的耐蚀性。sr - cap包覆的镁具有良好的细胞增殖和分化能力。此外，在体内证实了新骨的形成。因此，sr - cap涂层镁具有降低降解和改善生物相容性的特点，可用于骨科和牙科种植体应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biointerphases 生物-材料科学：生物材料

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期刊介绍： Biointerphases emphasizes quantitative characterization of biomaterials and biological interfaces. As an interdisciplinary journal, a strong foundation of chemistry, physics, biology, engineering, theory, and/or modelling is incorporated into originated articles, reviews, and opinionated essays. In addition to regular submissions, the journal regularly features In Focus sections, targeted on specific topics and edited by experts in the field. Biointerphases is an international journal with excellence in scientific peer-review. Biointerphases is indexed in PubMed and the Science Citation Index (Clarivate Analytics). Accepted papers appear online immediately after proof processing and are uploaded to key citation sources daily. The journal is based on a mixed subscription and open-access model: Typically, authors can publish without any page charges but if the authors wish to publish open access, they can do so for a modest fee. Topics include: bio-surface modification nano-bio interface protein-surface interactions cell-surface interactions in vivo and in vitro systems biofilms / biofouling biosensors / biodiagnostics bio on a chip coatings interface spectroscopy biotribology / biorheology molecular recognition ambient diagnostic methods interface modelling adhesion phenomena.