Opioid use disorder in cancer patients.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-06-01 Epub Date: 2023-03-03 DOI:10.1097/SPC.0000000000000640

Cara E S Lewis, John Schutzer-Weissmann, Paul Farquhar-Smith

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引用次数: 2

Abstract

Purpose of review: The misuse of opioids has increased significantly in recent decades. Historically, cancer patients have not been considered at risk of opioid misuse. However, cancer pain is common, and opioids are often prescribed. Guidelines addressing opioid misuse often exclude cancer patients. Given that misuse is associated with significant harm and a reduction in quality of life, it is important to understand the risk of opioid misuse in cancer patients and how we can recognise and treat it.

Recent findings: Early cancer diagnoses and treatments have improved cancer survival rates, leading to a larger population of cancer patients and survivors. Opioid use disorder (OUD) may precede a cancer diagnosis or may develop during or after treatment. The effect of OUD extends from an individual patient to a societal level. This review examines the increasing incidence of OUD in cancer patients, ways to identify patients with OUD such as behaviour change and screening scales, prevention of OUD such as limited and targeted opioid prescriptions, and evidence-based treatment suggestions for OUD.

Summary: OUD in cancer patients has only relatively recently been recognised as a growing problem. Early identification, involvement of the multidisciplinary team, and treatment can reduce the negative impact of OUD.

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癌症患者阿片类药物使用障碍。

审查目的：近几十年来，阿片类药物的滥用大幅增加。从历史上看，癌症患者没有被认为有滥用阿片类药物的风险。然而，癌症疼痛是常见的，阿片类药物通常是处方。针对阿片类药物滥用的指导方针通常将癌症患者排除在外。鉴于滥用与严重伤害和生活质量下降有关，了解癌症患者滥用阿片类药物的风险以及我们如何识别和治疗它是很重要的。最近的发现：癌症的早期诊断和治疗提高了癌症的存活率，导致更多的癌症患者和幸存者。阿片类药物使用障碍（OUD）可能发生在癌症诊断之前，也可能在治疗期间或治疗后发展。OUD的影响从个体患者延伸到社会层面。这篇综述研究了癌症患者OUD发病率的增加，识别OUD患者的方法，如行为改变和筛查量表，OUD的预防，如有限和有针对性的阿片类药物处方，以及OUD的循证治疗建议。早期识别、多学科团队的参与和治疗可以减少OUD的负面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.