Evaluation of morphine, methadone, digoxin, and dronabinol poisoning during the years 2017 to 2019 in Ilam, Iran.

Pub Date : 2023-01-01 DOI:10.22088/cjim.14.2.356
Kourosh Saki, Mahmoud Bahmani, Golnaz Zamanian, Naser Abbasi, Ali Aidy, Aliasghar Manouchehri, Sudip Kumar Mandal, Paramita Ganguly, Samira Shokri
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Abstract

Background: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam.

Methods: In this In this Cross-sectional study, patient samples suspected of morphine, methadone, digoxin, and dronabinol poisoning referred to the toxicology laboratory of Ilam University of Medical Sciences were analyzed using the HPLC method, and the results were analysed using SPSS software.

Results: Results showed that the percentage of drug use is greater in men than in women. The highest percentage of morphine and methadone poisonings were detected in those under the age of 40, whereas the highest percentage of digoxin poisonings were recorded in those over the age of 80. As a result, the average age of digoxin users was substantially greater in men than in women. Methadone consumers showed significantly greater blood levels than others. In addition, there was a significant difference (P<0.01) in blood levels between men and women who used morphine.

Conclusion: In general, it is important to understand the status of drug poisoning with drugs such as morphine, methadone, digoxin, and dronabinol, as well as the prognosis associated with the treatment process of such poisoning.

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2017 - 2019年伊朗伊拉姆地区吗啡、美沙酮、地高辛和屈大麻酚中毒的评价
背景:每年,药物中毒是患者转诊到医疗中心的最常见原因。本研究旨在评估伊拉姆沙希德·穆斯塔法·霍梅尼医院吗啡、美沙酮、地高辛和屈大麻酚中毒情况。方法:本横断面研究采用HPLC法对伊拉姆医科大学毒理学实验室疑似吗啡、美沙酮、地高辛、屈大麻酚中毒的患者样本进行分析,并采用SPSS软件对结果进行分析。结果:结果显示男性吸毒比例高于女性。40岁以下人群中吗啡和美沙酮中毒比例最高,80岁以上人群中地高辛中毒比例最高。因此,男性地高辛使用者的平均年龄明显大于女性。美沙酮服用者的血药浓度明显高于其他人。结论:总的来说,了解吗啡、美沙酮、地高辛、屈大麻酚等药物中毒的情况及其治疗过程与预后的关系是非常重要的。
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