Cognition in adults with borderline personality disorder.

IF 3.4 3区医学 Q2 CLINICAL NEUROLOGY

CNS Spectrums Pub Date : 2023-12-01 Epub Date: 2023-03-16 DOI:10.1017/S1092852923001177

Ibrahim H Aslan, Jon E Grant, Samuel R Chamberlain

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引用次数: 0

Abstract

Objective: Borderline personality disorder (BPD) is a common and disabling mental health disorder and has detrimental effects on affected individuals across multiple domains. We aimed to investigate whether individuals with BPD differ from control subjects in terms of cognitive functions, and to see if there is a relationship between cognitive functions, impulsivity, and BPD symptom severity.

Methods: BPD individuals (n = 26; mean age = 26.7; 69.2% female) and controls (n = 58; mean age = 25.3; 51.7% female) were enrolled. Intra/Extra-Dimensional Set Shift (IED) and One Touch Stockings of Cambridge (OTS) tasks from the Cambridge Neuropsychological Test Automated Battery (CANTAB) were used to assess cognitive functions. Barratt Impulsivity Scale-version 11 (BIS-11) was administered to measure impulsivity and both the Zanarini Scale for Borderline Personality Disorder self-report and the clinician-administered versions were used to assess BPD symptom severity.

Results: BPD group showed significantly impaired cognitive performance on the IED task versus controls, but there was not a significant difference in the OTS task. BPD symptom severity was positively correlated with trait (BIS-11) impulsivity and no correlation was found between BPD symptom severity and cognitive functions.

Conclusions: This study suggests people with BPD experience impaired cognitive flexibility and heightened impulsivity. Only impulsivity appeared to be directly related to symptom severity, perhaps indicating that cognitive inflexibility could be a vulnerability marker. Future research should focus on a longitudinal approach to extend clinical and theoretical knowledge in this area.

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边缘型人格障碍成人的认知。

目的：边缘型人格障碍（BPD）是一种常见的致残性精神疾病，对患者造成多方面的不利影响。我们旨在研究 BPD 患者在认知功能方面是否有别于对照组受试者，以及认知功能、冲动性和 BPD 症状严重程度之间是否存在关系：方法：研究人员招募了 BPD 患者（n = 26；平均年龄 = 26.7；69.2% 为女性）和对照组（n = 58；平均年龄 = 25.3；51.7% 为女性）。评估认知功能时使用了剑桥神经心理测试自动化电池（CANTAB）中的内/外维度集合移动（IED）和剑桥一触长袜（OTS）任务。巴拉特冲动性量表第11版（BIS-11）用于测量冲动性，边缘型人格障碍扎纳里尼量表自我报告版和临床医师管理版用于评估边缘型人格障碍症状的严重程度：结果：BPD组在IED任务中的认知表现明显低于对照组，但在OTS任务中没有明显差异。BPD症状严重程度与特质（BIS-11）冲动性呈正相关，而BPD症状严重程度与认知功能之间未发现相关性：本研究表明，BPD 患者的认知灵活性受损，冲动性增强。只有冲动性似乎与症状严重程度直接相关，这或许表明认知灵活性不足可能是一种易感性标志。未来的研究应侧重于纵向方法，以扩展这一领域的临床和理论知识。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

CNS Spectrums 医学-精神病学

CiteScore

6.20

自引率

6.10%

发文量

239

审稿时长

>12 weeks

期刊介绍： CNS Spectrums covers all aspects of the clinical neurosciences, neurotherapeutics, and neuropsychopharmacology, particularly those pertinent to the clinician and clinical investigator. The journal features focused, in-depth reviews, perspectives, and original research articles. New therapeutics of all types in psychiatry, mental health, and neurology are emphasized, especially first in man studies, proof of concept studies, and translational basic neuroscience studies. Subject coverage spans the full spectrum of neuropsychiatry, focusing on those crossing traditional boundaries between neurology and psychiatry.