Personalized Medicine: Advanced Treatment Strategies to Revolutionize Healthcare.

Q3 Medicine
Arun Kumar Singh, Rishabha Malviya, Swati Verma
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引用次数: 0

Abstract

Personalized medicine (PM) is about developing an individualized approach to each patient's illness. Understanding how a patient's genomic portfolio renders them prone to various diseases may be enhanced by discovering genetic, epigenetic, and medical evidence. Medical therapy that is safe and effective for specific individuals may be predicted using the PM approach, which is a complete expansion of an older methodology (One-Size-Fits-All). Patient's well-being and longevity may improve and costs are reduced if PM is used. Using existing biomarkers and early genome and epigenomic processes to better understand PM may lead to earlier diagnosis of the disease, including carcinogenesis. A key focus of the PM technique is preventative medicine, which emphasizes proactive actions rather than depending only on reactive ones. More intrusive procedures may be avoided or postponed using this technique, resulting in a higher quality of life and lower financial burdens for patients. End-of-life care costs are putting a strain on governmentfunded healthcare systems across the globe, notably in the United States. When used in conjunction with present treatments, PM may help them work better and lessen the disadvantages of just non-PM methods. Using genetic profiling, doctors may choose a drug based on a participant's genetic profile that minimizes unwanted side effects and ensures a better result while also being less costly than a 'trial-and-error' approach to sickness treatment. The less effective non- PM ('trial-and-error') strategy leads to drug toxicity, severe adverse effects, reactive treatment, and misdiagnosis. PM and proactive therapeutic regimens should be used more often to save costs and enhance overall well-being.

个性化医疗:革新医疗保健的先进治疗策略。
个性化医疗(PM)是针对每个病人的疾病制定个性化的治疗方法。通过发现遗传、表观遗传和医学证据,可以进一步了解患者的基因组组合如何使他们容易患上各种疾病。可以使用PM方法预测对特定个体安全有效的医学治疗,这是旧方法(一刀切)的完全扩展。如果使用PM,可能会改善患者的健康和寿命,并降低成本。利用现有的生物标志物和早期基因组和表观基因组过程来更好地了解PM可能导致疾病的早期诊断,包括癌变。项目管理技术的一个重点是预防医学,它强调主动的行动,而不是仅仅依赖于被动的行动。使用这种技术可以避免或推迟更多的侵入性手术,从而提高患者的生活质量,减轻患者的经济负担。临终关怀费用给全球政府资助的医疗保健系统带来了压力,尤其是在美国。当与现有的治疗方法结合使用时,PM可以帮助它们更好地工作,并减少非PM方法的缺点。利用基因图谱,医生可以根据参与者的基因图谱选择一种药物,以最大限度地减少不必要的副作用,确保更好的结果,同时也比“反复试验”的疾病治疗方法成本更低。效果较差的非PM(“试错”)策略导致药物毒性、严重不良反应、反应性治疗和误诊。应该更经常地使用PM和主动治疗方案,以节省成本并提高整体福祉。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Drug Research Reviews
Current Drug Research Reviews Medicine-Psychiatry and Mental Health
CiteScore
3.70
自引率
0.00%
发文量
38
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