Hyperferritinemic sepsis secondary to invasive Toxoplasma gondii in a child with untreated HIV.

IF 0.6 Q4 PEDIATRICS
Jesús Domínguez-Rojas, Jackeline Caute-Lara, Patrick Caqui-Vilca, Mario Cruz-Arpi, Carlos Martel-Ramírez, Miguel Quispe-Chipana, Abel Sánchez-Rodríguez, Noé Atamari-Anahui
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引用次数: 0

Abstract

Background: Untreated human immunodeficiency virus (HIV)-immunosuppressed pediatric patients show high morbidity and mortality from opportunistic infections. Limited cases of hyperferritinemic sepsis have been described in patients with toxoplasmosis.

Case report: We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution.

Conclusions: The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications.

未经治疗的HIV患儿侵袭性刚地弓形虫继发的高铁素血症败血症。
背景:未经治疗的人类免疫缺陷病毒(HIV)免疫抑制的儿科患者机会性感染的发病率和死亡率很高。有限的情况下,高铁血症败血症已描述在患者弓形虫病。病例报告:我们描述了一个13岁的女性患者与未经治疗的HIV史谁提出了高铁蛋白血症败血症继发弓形虫感染和肺囊虫肺炎。她接受了呼吸机支持、肌力药物、机会性细菌治疗和大剂量皮质类固醇治疗,但进展不利。结论:铁蛋白升高的脓毒症的全球方法指导使用旨在中和严重炎症反应的治疗方法。及时的诊断可以及时治疗并减少并发症。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
73
审稿时长
20 weeks
期刊介绍: The Boletín Médico del Hospital Infantil de México is a bimonthly publication edited by the Hospital Infantil de México Federico Gómez. It receives unpublished manuscripts, in English or Spanish, relating to paediatrics in the following areas: biomedicine, clinical, public health, clinical epidemology, health education and clinical ethics. Articles can be original research articles, in-depth or systematic reviews, clinical cases, clinical-pathological cases, articles about public health, letters to the editor or editorials (by invitation).
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