Shunt Nephritis: A Case of Mistaken Identity.

IF 1.6 4区 医学 Q2 Medicine
Tim Van Damme, Nic Veys, Marijn M Speeckaert, Sigurd E Delanghe
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引用次数: 0

Abstract

Background: Membranoproliferative glomerulonephritis is a histological pattern of glomerular injury due to the deposition of immune complexes and complement factors. It is associated with bacterial and viral infections, auto-immune diseases such as systemic lupus erythematosus and Sjögren's syndrome, monoclonal gammopathy, and complement disorders (dense deposit disease and C3 glomerulopathy).  Case presentation: This is the report of a 25-year-old male with membranoproliferative glomerulonephritis who was initially treated for systemic lupus erythematosus, but who was later diagnosed with nephritis due to a chronic infection of a central nervous system shunt, last revised at the age of 3 years old.

Discussion: We highlight the challenges in making an early diagnosis of shunt nephritis, and succinctly discuss the clinical, biochemical, histopathological findings, and differential diagnosis of this type of infection-related glomerulonephritis.

分流性肾炎:误诊一例。
背景:膜增生性肾小球肾炎是一种由免疫复合物和补体因子沉积引起的肾小球损伤的组织学模式。它与细菌和病毒感染、自身免疫性疾病(如系统性红斑狼疮和Sjögren综合征)、单克隆伽玛病和补体疾病(致密沉积病和C3肾小球病)有关。病例报告:这是一个25岁的男性膜增生性肾小球肾炎,最初治疗系统性红斑狼疮,但后来被诊断为肾炎,由于慢性感染中枢神经系统分流,最后修改在3岁时。讨论:我们强调在早期诊断分流性肾炎的挑战,并简要讨论临床,生化,组织病理学的结果,和鉴别诊断的这种类型的感染相关的肾小球肾炎。
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来源期刊
Acta Clinica Belgica
Acta Clinica Belgica 医学-医学:内科
CiteScore
2.90
自引率
0.00%
发文量
44
审稿时长
6-12 weeks
期刊介绍: Acta Clinica Belgica: International Journal of Clinical and Laboratory Medicine primarily publishes papers on clinical medicine, clinical chemistry, pathology and molecular biology, provided they describe results which contribute to our understanding of clinical problems or describe new methods applicable to clinical investigation. Readership includes physicians, pathologists, pharmacists and physicians working in non-academic and academic hospitals, practicing internal medicine and its subspecialties.
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