Association between cardiac conditions with venous leg ulcers in patients with chronic venous insufficiency.

IF 1.6 4区医学 Q3 PERIPHERAL VASCULAR DISEASE

Phlebology Pub Date : 2023-05-01 DOI:10.1177/02683555231162294

Alejandro Pizano, Beau Bequeaith, Sebastian Cifuentes, Valentin Figueroa, Haider Al Rustem, Hunter M Ray, Sheila Coogan, Charles Miller, Jorge H Ulloa, Stuart A Harlin

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引用次数: 1

Abstract

Introduction: Venous leg ulcers (VLUs) are the final stage of chronic venous insufficiency. This study aims to characterize the association between cardiovascular diseases and VLU.

Methods: A multicentric case-control study analyzed 17,788 patients between 2015 and 2020. Cases were matched (1:2) by age and sex, and odds ratios (OR) were analyzed with conditional logistic regressions adjusted by risk factors.

Results: The prevalence of VLU was 15.2%. 2390 cases were analyzed. Diseases found to be associated with VLU were atrial fibrillation (OR, 1.21; 95% CI: 1.03-1.42), pulmonary hypertension (OR, 1.45; 95% CI: 1.06-2.00), right heart failure (OR, 1.27; 95% CI: 1.13-1.43), peripheral artery disease (OR, 2.21; 95% CI: 1.90-2.56), and history of pulmonary embolism (OR, 1.45; 95% CI: 1.06-2.00).

Conclusions: Certain cardiovascular conditions showed an association with VLU. Further studies are warranted to evaluate the effect that treating concomitant cardiovascular diseases might exert on the natural history of venous leg ulcers.

查看原文本刊更多论文

慢性静脉功能不全患者的心脏状况与下肢静脉溃疡之间的关系。

下肢静脉溃疡(VLUs)是慢性静脉功能不全的最后阶段。本研究旨在探讨心血管疾病与VLU之间的关系。方法:2015年至2020年，一项多中心病例对照研究分析了17788例患者。病例按年龄和性别匹配(1:2)，并通过危险因素调整后的条件logistic回归分析比值比(OR)。结果:VLU患病率为15.2%。共分析病例2390例。与VLU相关的疾病有房颤(OR, 1.21;95% CI: 1.03-1.42)，肺动脉高压(OR, 1.45;95% CI: 1.06-2.00)，右心衰(OR, 1.27;95% CI: 1.13-1.43)，外周动脉疾病(OR, 2.21;95% CI: 1.90-2.56)和肺栓塞史(OR, 1.45;95% ci: 1.06-2.00)。结论:某些心血管疾病与VLU有关。需要进一步的研究来评估治疗伴发心血管疾病可能对静脉性腿溃疡自然史的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Phlebology 医学-外周血管病

CiteScore

3.30

自引率

11.80%

发文量

审稿时长

6-12 weeks

期刊介绍： The leading scientific journal devoted entirely to venous disease, Phlebology is the official journal of several international societies devoted to the subject. It publishes the results of high quality studies and reviews on any factor that may influence the outcome of patients with venous disease. This journal provides authoritative information about all aspects of diseases of the veins including up to the minute reviews, original articles, and short reports on the latest treatment procedures and patient outcomes to help medical practitioners, allied health professionals and scientists stay up-to-date on developments. Print ISSN: 0268-3555