Growing importance of brain morphometry analysis in the clinical routine: The hidden impact of MR sequence parameters

IF 3 3区 医学 Q2 CLINICAL NEUROLOGY
Michael Rebsamen , Milena Capiglioni , Robert Hoepner , Anke Salmen , Roland Wiest , Piotr Radojewski , Christian Rummel
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引用次数: 0

Abstract

Volumetric assessment based on structural MRI is increasingly recognized as an auxiliary tool to visual reading, also in examinations acquired in the clinical routine. However, MRI acquisition parameters can significantly influence these measures, which must be considered when interpreting the results on an individual patient level.

This Technical Note shall demonstrate the problem. Using data from a dedicated experiment, we show the influence of two crucial sequence parameters on the GM/WM contrast and their impact on the measured volumes. A simulated contrast derived from acquisition parameters TI/TR may serve as surrogate and is highly correlated (r=0.96) with the measured contrast.

Abstract Image

Abstract Image

脑形态分析在临床常规工作中的重要性与日俱增:磁共振序列参数的隐性影响
在临床常规检查中,基于结构性核磁共振成像的容积评估越来越多地被认为是肉眼判读的辅助工具。然而,核磁共振成像采集参数会对这些测量结果产生重大影响,在解释个体患者的结果时必须考虑到这一点。我们利用专门实验的数据,展示了两个关键序列参数对 GM/WM 对比度的影响及其对测量体积的影响。根据采集参数 TI/TR 得出的模拟对比度可作为替代对比度,与测量对比度高度相关(r=0.96)。
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来源期刊
Journal of Neuroradiology
Journal of Neuroradiology 医学-核医学
CiteScore
6.10
自引率
5.70%
发文量
142
审稿时长
6-12 weeks
期刊介绍: The Journal of Neuroradiology is a peer-reviewed journal, publishing worldwide clinical and basic research in the field of diagnostic and Interventional neuroradiology, translational and molecular neuroimaging, and artificial intelligence in neuroradiology. The Journal of Neuroradiology considers for publication articles, reviews, technical notes and letters to the editors (correspondence section), provided that the methodology and scientific content are of high quality, and that the results will have substantial clinical impact and/or physiological importance.
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