Treatment Outcome of Occlusion for Unilateral Amblyopia in Saudi Children 6-12 Years Old.

IF 0.5 Q4 OPHTHALMOLOGY
Gorka Sesma, Tasnim AlMairi, Heba Khashoggi, Fahad Aljohar, Rajiv Khandekar, Abdulaziz Awad
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Abstract

Purpose: The purpose of this study was to estimate the rate and review determinants of successful therapy for unilateral amblyopia in children.

Methods: This prospective cohort consisted of Saudi children aged 6-12 who received amblyopia therapy between 2020 and 2022. Best-corrected visual acuity (BCVA) in the amblyopic eye improved to reach the BCVA of the fellow eye at follow-up visits, or BCVA in the amblyopic eye improved and remained stable over three follow-up visits. Demographic and ocular characteristics were associated with the outcome.

Results: In 30 children, the median BCVA at presentation and the last follow-up was 0.8 logMAR (interquartile range [IQR]: 0.6; 1.0) and 0.45 logMAR (IQR: 0.3; 0.6), respectively. The success rate of amblyopia therapy was 80% (95% confidence interval: 65.7; 94.3). It was 100%, 76.5%, and 77.8% in eyes with anisometropic, strabismic, and mixed types of amblyopia, respectively. Amblyopia grade (P = 0.177), type of amblyopia (P = 0.96), and spectacles as therapy in the past (P = 0.09) were not significantly associated with the successful out. The duration of follow-up was significantly longer in those with unsuccessful outcomes (P = 0.05). Excellent compliance for occlusion was observed in 62.5% of children with successful outcomes. In 14 (46.7%) children, BCVA was ≤0.3 logMAR BCVA at the last follow-up. Two-line improvement in amblyopic eyes was in 26 (86.7%) children at the last follow-up compared to BCVA at presentation.

Conclusion: Occlusion therapy complemented using glasses in older children also significantly improved visual recovery in amblyopic eyes.

Abstract Image

沙特6-12岁儿童单侧弱视的闭塞治疗效果。
目的:本研究的目的是估计儿童单侧弱视成功治疗的比率和回顾决定因素。方法:该前瞻性队列包括在2020年至2022年期间接受弱视治疗的6-12岁沙特儿童。弱视眼的最佳矫正视力(BCVA)改善,在随访时达到同眼的BCVA,或弱视眼的BCVA改善并在三次随访中保持稳定。人口统计学和眼部特征与结果相关。结果:30例患儿就诊时和最后一次随访时的中位BCVA为0.8 logMAR(四分位数间距[IQR]: 0.6;1.0)和0.45 logMAR (IQR: 0.3;分别为0.6)。弱视治疗成功率为80%(95%可信区间:65.7;94.3)。屈光参差型、斜视型和混合型弱视分别为100%、76.5%和77.8%。弱视等级(P = 0.177)、弱视类型(P = 0.96)、是否配戴过眼镜(P = 0.09)与成功出院无显著相关性。治疗不成功者随访时间明显延长(P = 0.05)。62.5%的患儿具有良好的咬合依从性。14例(46.7%)患儿在最后一次随访时BCVA≤0.3 logMAR。与首发时的BCVA相比,在最后一次随访中,26名(86.7%)儿童的弱视有两线改善。结论:遮挡治疗配合眼镜治疗可显著改善儿童弱视的视力恢复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
1
期刊介绍: The Middle East African Journal of Ophthalmology (MEAJO), published four times per year in print and online, is an official journal of the Middle East African Council of Ophthalmology (MEACO). It is an international, peer-reviewed journal whose mission includes publication of original research of interest to ophthalmologists in the Middle East and Africa, and to provide readers with high quality educational review articles from world-renown experts. MEAJO, previously known as Middle East Journal of Ophthalmology (MEJO) was founded by Dr Akef El Maghraby in 1993.
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