Freja LÆrke Sand, Louise T Thomsen, Dorthe Oernskov, Christian Munk, Marianne Waldstroem, Susanne K Kjaer
{"title":"Cervical human papillomavirus prevalence according to socioeconomic and demographic characteristics in a large Danish screening population.","authors":"Freja LÆrke Sand, Louise T Thomsen, Dorthe Oernskov, Christian Munk, Marianne Waldstroem, Susanne K Kjaer","doi":"10.1177/14034948231168297","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to investigate high-risk human papillomavirus (hrHPV) prevalence according to socioeconomic and demographic characteristics in a Danish screening population.</p><p><strong>Methods: </strong>We used data from HPV SCREEN DENMARK, which was an implementation study embedded into the routine cervical cancer screening programme. During 2017-2020, women aged 30-59 years screened in the Region of Southern Denmark were offered HPV testing or cytology. In the HPV group, liquid-based cytology samples were tested for 14 hrHPV types. We obtained registry information on socioeconomic and demographic characteristics and used log-binomial regression to estimate the prevalence ratio (PR) of hrHPV in three age groups (30-39, 40-49, 50-59 years), adjusting for age and marital status.</p><p><strong>Results: </strong>We included 31,124 HPV unvaccinated women. In all age groups, the age-adjusted hrHPV prevalence was higher in women with basic versus higher education (e.g. age 30-39: 11.9% <i>vs</i>. 9.5%; PR<sub>age-adjusted</sub>=1.24; 95% confidence interval (CI): 1.02-1.50); women who were unemployed <i>vs</i>. employed (e.g. age 30-39: 11.6% <i>vs</i>. 10.4%; PR<sub>age-adjusted</sub>=1.11; 95% CI: 0.95-1.28); and in women with highest <i>vs</i>. lowest income (e.g. age 30-39: 11.6% <i>vs</i>. 9.5%, PR<sub>age-adjusted</sub>=1.18, 95% CI: 0.98-1.44). In models adjusted for marital status, these associations largely disappeared.</p><p><strong>Conclusions: </strong>\n <b>We found slightly higher hrHPV prevalences in women with basic education, low income and unemployment. The differences largely disappeared when taking into account marital status as a potential proxy for sexual behaviour. Our findings support a need for targeted information on safe sexual practices and promoting socioeconomic equality in HPV vaccination and cervical cancer screening participation.</b>\n </p>","PeriodicalId":49568,"journal":{"name":"Scandinavian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian Journal of Public Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/14034948231168297","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/4/20 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
Aim: The aim of this study was to investigate high-risk human papillomavirus (hrHPV) prevalence according to socioeconomic and demographic characteristics in a Danish screening population.
Methods: We used data from HPV SCREEN DENMARK, which was an implementation study embedded into the routine cervical cancer screening programme. During 2017-2020, women aged 30-59 years screened in the Region of Southern Denmark were offered HPV testing or cytology. In the HPV group, liquid-based cytology samples were tested for 14 hrHPV types. We obtained registry information on socioeconomic and demographic characteristics and used log-binomial regression to estimate the prevalence ratio (PR) of hrHPV in three age groups (30-39, 40-49, 50-59 years), adjusting for age and marital status.
Results: We included 31,124 HPV unvaccinated women. In all age groups, the age-adjusted hrHPV prevalence was higher in women with basic versus higher education (e.g. age 30-39: 11.9% vs. 9.5%; PRage-adjusted=1.24; 95% confidence interval (CI): 1.02-1.50); women who were unemployed vs. employed (e.g. age 30-39: 11.6% vs. 10.4%; PRage-adjusted=1.11; 95% CI: 0.95-1.28); and in women with highest vs. lowest income (e.g. age 30-39: 11.6% vs. 9.5%, PRage-adjusted=1.18, 95% CI: 0.98-1.44). In models adjusted for marital status, these associations largely disappeared.
Conclusions: We found slightly higher hrHPV prevalences in women with basic education, low income and unemployment. The differences largely disappeared when taking into account marital status as a potential proxy for sexual behaviour. Our findings support a need for targeted information on safe sexual practices and promoting socioeconomic equality in HPV vaccination and cervical cancer screening participation.
期刊介绍:
The Scandinavian Journal of Public Health is an international peer-reviewed journal which has a vision to: publish public health research of good quality; contribute to the conceptual and methodological development of public health; contribute to global health issues; contribute to news and overviews of public health developments and health policy developments in the Nordic countries; reflect the multidisciplinarity of public health.