How Does the Urethra Respond to Bladder Filling in Continent and Incontinent Women?

IF 1.4 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Female Pelvic Medicine and Reconstructive Surgery Pub Date : 2022-05-01 Epub Date: 2021-12-03 DOI:10.1097/SPV.0000000000001125

Julia Geynisman-Tan, Tsung Mou, Margaret G Mueller, Kimberly Kenton

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引用次数: 0

Abstract

Objective: The objective of this study was to describe mean urethral pressure (MUP) during filling cystometry in continent and incontinent women.

Methods: Incontinent women were recruited from a urogynecology clinic if they answered "sometimes" or "always" to 1 of the items on the Medical, Epidemiologic, and Social Aspects of Aging questionnaire. Participants were categorized by Medical, Epidemiologic, and Social Aspects of Aging scores into stress urinary incontinence (SUI) or urgency urinary incontinence (UUI) groups. Continent women were recruited from the community. Multichannel urodynamics were performed using microtip catheters. Urethral pressure profiles were obtained with an empty bladder and at 100-mL increments during filling. Data were analyzed in SPSS. Continuous variables were compared with independent t test or analysis of variance, categorical variables with the χ2 test, and multivariable comparisons were made with linear regression.

Results: Eighty-six women (30 continent, 56 incontinent: 37 SUI, 19 UUI) with a mean ± SD age of 48 ± 15 years and a body mass index (BMI) of 31 ± 9 participated. Sixty-nine percent were White, 43% were postmenopausal, and 80% were parous. Continent women were younger (P < 0.001) and had a lower BMI (P = 0.004). Mean cystometric capacity was higher in women with SUI and continent women than in women with UUI (430 ± 142, 448 ± 101, and 332 ± 160, P = 0.04). Continent women had higher MUP at baseline when controlling for age, BMI, and parity (84 ± 35 cmH2O vs 62 ± 28 cmH2O; aR2 = 0.2, P = 0.02) compared with incontinent women. During filling, MUP in continent women was 20-30 cmH2O higher at all bladder volumes than incontinent women. Mean urethral pressure increased significantly between baseline and 300 mL in continent women (P < 0.005) and women with SUI (P = 0.04), but not in women with UUI (P = 0.48).

Conclusions: Continent women have greater baseline MUP and greater increases in MUP during bladder filling than incontinent women.

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尿失禁和大便失禁妇女的尿道对膀胱充盈有何反应？

研究目的本研究旨在描述失禁和失禁妇女在充盈膀胱测量过程中的平均尿道压（MUP）：方法：从泌尿妇科诊所招募尿失禁妇女，只要她们对 "老龄化的医学、流行病学和社会方面 "问卷中的一项回答 "有时 "或 "总是"。根据医学、流行病学和社会老龄化方面的评分，将参与者分为压力性尿失禁（SUI）组和急迫性尿失禁（UUI）组。大洲妇女是从社区招募的。使用微尖导尿管进行多通道尿动力学检查。在空膀胱和充盈时以 100 毫升为单位获取尿道压力曲线。数据用 SPSS 进行分析。连续变量的比较采用独立 t 检验或方差分析，分类变量的比较采用 χ2 检验，多变量比较采用线性回归：参加研究的 86 名女性（30 名失禁，56 名失禁：37 名 SUI，19 名 UUI）的平均年龄为 48±15 岁，体重指数（BMI）为 31±9 。69%为白人，43%为绝经后妇女，80%为parous。大陆女性更年轻（P < 0.001），体重指数更低（P = 0.004）。SUI 和大便失禁妇女的平均膀胱容量高于 UUI 妇女（430 ± 142、448 ± 101 和 332 ± 160，P = 0.04）。在控制年龄、体重指数（BMI）和胎次的情况下，与失禁女性相比，大便失禁女性的基线 MUP 较高（84 ± 35 cmH2O vs 62 ± 28 cmH2O；aR2 = 0.2，P = 0.02）。充盈期间，在所有膀胱容量下，失禁女性的 MUP 均比失禁女性高 20-30 cmH2O。在基线和 300 毫升之间，失禁女性和 SUI 女性的平均尿道压明显增加（P < 0.005），但 UUI 女性的平均尿道压没有增加（P = 0.48）：结论：与尿失禁女性相比，大便失禁女性的基线 MUP 更大，膀胱充盈时 MUP 的增幅也更大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Female Pelvic Medicine and Reconstructive Surgery OBSTETRICS & GYNECOLOGY-

CiteScore

2.10

自引率

12.50%

发文量

228

期刊介绍： Female Pelvic Medicine & Reconstructive Surgery, official journal of the American Urogynecologic Society, is a peer-reviewed, multidisciplinary journal dedicated to specialists, physicians and allied health professionals concerned with prevention, diagnosis and treatment of female pelvic floor disorders. The journal publishes original clinical research, basic science research, education, scientific advances, case reports, scientific reviews, editorials and letters to the editor.