Examining the role of the uncinate fasciculus in proper noun naming: awake brain tumor resections and stereo EEG targeted electrical stimulation multiple case study.

IF 0.6 4区医学 Q4 CLINICAL NEUROLOGY

Neurocase Pub Date : 2022-10-01 DOI:10.1080/13554794.2022.2160261

Jun Min Koay, Karen E Blackmon, Erik H Middlebrooks, Alfredo Quinones-Hinojosa, Kaisorn L Chaichana, Anteneh M Feyissa, Sanjeet S Grewal, David S Sabsevitz

引用次数: 1

Abstract

While there is strong evidence from lesion and functional imaging studies implicating the left anterior temporal pole (LTP) in naming unique entities, less is known about white matter tracts in category-specific naming. We present evidence that implicates the uncinate fasciculus (UF) in proper noun naming. First, we describe two patients with left LTP gliomas who developed category specific worsening in proper noun naming in real time during awake surgery when the UF was surgically involved . We then describe a third case involving targeted electrical stimulation of the UF using stereo-electroencephalography (sEEG) that resulted in category specific naming disturbance for proper nouns..

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探讨钩扣束在专有名词命名中的作用:清醒脑肿瘤切除和立体脑电图定向电刺激多例研究。

虽然有来自病变和功能成像研究的有力证据表明，左颞叶前极(LTP)与命名独特实体有关，但对白质束在特定类别命名中的作用知之甚少。我们提出的证据暗示钩状束(UF)在专有名词命名。首先，我们描述了两例左侧LTP胶质瘤患者，当手术涉及UF时，他们在清醒手术期间实时出现专有名词命名类别特异性恶化。然后，我们描述了第三个案例，涉及使用立体脑电图(sEEG)对UF进行有针对性的电刺激，导致专有名词的类别特定命名障碍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurocase 医学-精神病学

CiteScore

1.40

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.