Information and Communication Theoretical Understanding and Treatment of Spinal Cord Injuries: State-of-The-Art and Research Challenges

IF 17.2 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL
Ozgur B. Akan;Hamideh Ramezani;Meltem Civas;Oktay Cetinkaya;Bilgesu A. Bilgin;Naveed A. Abbasi
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引用次数: 10

Abstract

Among the various key networks in the human body, the nervous system occupies central importance. The debilitating effects of spinal cord injuries (SCI) impact a significant number of people throughout the world, and to date, there is no satisfactory method to treat them. In this paper, we review the major treatment techniques for SCI that include promising solutions based on information and communication technology (ICT) and identify the key characteristics of such systems. We then introduce two novel ICT-based treatment approaches for SCI. The first proposal is based on neural interface systems (NIS) with enhanced feedback, where the external machines are interfaced with the brain and the spinal cord such that the brain signals are directly routed to the limbs for movement. The second proposal relates to the design of self-organizing artificial neurons (ANs) that can be used to replace the injured or dead biological neurons. Apart from SCI treatment, the proposed methods may also be utilized as enabling technologies for neural interface applications by acting as bio-cyber interfaces between the nervous system and machines. Furthermore, under the framework of Internet of Bio-Nano Things (IoBNT), experience gained from SCI treatment techniques can be transferred to nano communication research.
信息与通信理论对脊髓损伤的理解和治疗:最新技术和研究挑战
在人体的各种关键网络中,神经系统占据着核心地位。脊髓损伤(SCI)的衰弱影响着全世界相当多的人,到目前为止,还没有令人满意的治疗方法。在本文中,我们回顾了SCI的主要治疗技术,包括基于信息和通信技术(ICT)的有前景的解决方案,并确定了这些系统的关键特征。然后,我们介绍了两种新的基于ICT的SCI治疗方法。第一个方案是基于具有增强反馈的神经接口系统(NIS),其中外部机器与大脑和脊髓接口,使得大脑信号直接路由到肢体进行运动。第二项提案涉及自组织人工神经元(AN)的设计,可用于替换受伤或死亡的生物神经元。除了SCI治疗外,所提出的方法还可以通过充当神经系统和机器之间的生物网络接口,作为神经接口应用的使能技术。此外,在生物纳米物联网(IoBNT)的框架下,从SCI治疗技术中获得的经验可以转移到纳米通信研究中。
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来源期刊
IEEE Reviews in Biomedical Engineering
IEEE Reviews in Biomedical Engineering Engineering-Biomedical Engineering
CiteScore
31.70
自引率
0.60%
发文量
93
期刊介绍: IEEE Reviews in Biomedical Engineering (RBME) serves as a platform to review the state-of-the-art and trends in the interdisciplinary field of biomedical engineering, which encompasses engineering, life sciences, and medicine. The journal aims to consolidate research and reviews for members of all IEEE societies interested in biomedical engineering. Recognizing the demand for comprehensive reviews among authors of various IEEE journals, RBME addresses this need by receiving, reviewing, and publishing scholarly works under one umbrella. It covers a broad spectrum, from historical to modern developments in biomedical engineering and the integration of technologies from various IEEE societies into the life sciences and medicine.
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