Magnetic nanoparticles: multifunctional tool for cancer therapy.

IF 5 2区医学 Q1 PHARMACOLOGY & PHARMACY

Expert Opinion on Drug Delivery Pub Date : 2023-02-01 DOI:10.1080/17425247.2023.2166484

Sumera Khizar, Eslam Elkalla, Nadia Zine, Nicole Jaffrezic-Renault, Abdelhamid Errachid, Abdelhamid Elaissari

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引用次数: 4

Abstract

Introduction: Cancer has one of the highest mortality rates globally. The traditional therapies used to treat cancer have harmful adverse effects. Considering these facts, researchers have explored new therapeutic possibilities with enhanced benefits. Nanoparticle development for cancer detection, in addition to therapy, has shown substantial progress over the past few years.

Area covered: Herein, the latest research regarding cancer treatment employing magnetic nanoparticles (MNPs) in chemo-, immuno-, gene-, and radiotherapy along with hyperthermia is summarized, in addition to their physio-chemical features, advantages, and limitations for clinical translation have also been discussed.

Expert opinion: MNPs are being extensively investigated and developed into effective modules for cancer therapy. They are highly functional tools aimed at cancer therapy owing to their excellent superparamagnetic, chemical, biocompatible, physical, and biodegradable properties.

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磁性纳米颗粒:癌症治疗的多功能工具。

导言:癌症是全球死亡率最高的疾病之一。用于治疗癌症的传统疗法有有害的副作用。考虑到这些事实，研究人员已经探索了新的治疗可能性，并提高了疗效。除了治疗之外，用于癌症检测的纳米粒子发展在过去几年中取得了实质性进展。涉及领域:本文综述了磁性纳米颗粒(MNPs)在化疗、免疫、基因和放疗以及热疗中治疗癌症的最新研究，并讨论了它们的理化特征、优势和临床转化的局限性。专家意见:正在对MNPs进行广泛研究，并将其开发为癌症治疗的有效模块。由于其优异的超顺磁性、化学、生物相容性、物理和可生物降解特性，它们是针对癌症治疗的高功能工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Opinion on Drug Delivery 医学-药学

CiteScore

11.10

自引率

3.00%

发文量

104

审稿时长

3 months

期刊介绍： Expert Opinion on Drug Delivery (ISSN 1742-5247 [print], 1744-7593 [electronic]) is a MEDLINE-indexed, peer-reviewed, international journal publishing review articles covering all aspects of drug delivery research, from initial concept to potential therapeutic application and final relevance in clinical use. Each article is structured to incorporate the author’s own expert opinion on the scope for future development.