Factors related to the development of executive functions: A cumulative dopamine genetic score and environmental factors predict performance of kindergarten children in a go/nogo task
Marie Fiedler , Carmen Hofmann , Christian Montag , Markus Kiefer
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引用次数: 0
Abstract
Background
This study aimed at investigating the interaction between genetic and environmental factors in predicting executive function in children aged four to six years.
Methods
Response inhibition as index of EF was assessed in 197 children using a go/nogo task. A cumulative dopamine (DA) genetic score was calculated, indexing predisposition of low DA activity. Dimensions of parenting behavior and parental education were assessed.
Results
Parental education was positively related to accuracy in nogo trials. An interaction between the cumulative genetic score and the parenting dimension Responsiveness predicted go RT indicating that children with a high cumulative genetic score and high parental responsiveness exhibited a careful response mode.
Conclusion
The development of EF in kindergarten children is related to parental education as well as to an interaction between the molecular-genetics of the DA system and parenting behavior.