Updates in the diagnosis and management of Takayasu's arteritis.

IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Anupam Somashekar, Yiu Tak Leung
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引用次数: 1

Abstract

Takayasu's arteritis is a rare, chronic, large vessel vasculitis which affects the aorta and its large branches. Early diagnosis is important to prevent serious end organ damage, including to stroke and ischemic heart disease. Studies have demonstrated treatment response with methotrexate, azathioprine, and tumor necrosis factor (TNF) inhibitors. This article aims to describe to the reader key features of Takayasu's arteritis and highlights updated evidence in the diagnosis and management of these patients. We also review the 2021 ACR guidelines for Takayasu's arteritis and correlate them to the updated evidence discussed throughout the review. An extensive literature search was conducted via PUBMED, including the words 'Takayasu's diagnostic criteria,' 'Takayasu's treatment,' 'Takayasu's diagnosis,' 'Takayasu's imaging', and 'Takayasu's diagnostic criteria.' Search was filtered to include clinical trials, randomized controlled trials, systematic reviews, and meta-analyses. Articles in the English language or with English translation and published by the date of 20 December 2021 were included.

Takayasu动脉炎的诊断和治疗进展。
高松动脉炎是一种罕见的慢性大血管炎,主要累及主动脉及其大分支。早期诊断对于预防严重的终末器官损伤,包括中风和缺血性心脏病非常重要。研究表明甲氨蝶呤、硫唑嘌呤和肿瘤坏死因子(TNF)抑制剂有治疗效果。本文旨在向读者描述高松动脉炎的主要特征,并强调这些患者的诊断和治疗的最新证据。我们还回顾了Takayasu动脉炎的2021年ACR指南,并将其与整个综述中讨论的最新证据联系起来。通过PUBMED进行了广泛的文献检索,包括“Takayasu的诊断标准”、“Takayasu的治疗”、“Takayasu的诊断”、“Takayasu的成像”和“Takayasu的诊断标准”等词。检索经过筛选,包括临床试验、随机对照试验、系统评价和荟萃分析。纳入了在2021年12月20日之前发表的英文或有英文翻译的文章。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Postgraduate Medicine
Postgraduate Medicine 医学-医学:内科
CiteScore
6.10
自引率
2.40%
发文量
110
审稿时长
6-12 weeks
期刊介绍: Postgraduate Medicine is a rapid peer-reviewed medical journal published for physicians. Tracing its roots back to 1916,  Postgraduate Medicine  was established by Charles Mayo, MD, as a peer-to-peer method of communicating the latest research to aid physicians when making treatment decisions, and it maintains that aim to this day. In addition to its core subscriber base, Postgraduate Medicine is distributed to hundreds of US-based physicians within internal medicine and family practice.
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