The Bridging Effect of Artificial Dermis on Reconstruction of Skin Avulsion Injury.

IF 1.5 4区医学 Q3 DERMATOLOGY

International Journal of Lower Extremity Wounds Pub Date : 2025-12-01 Epub Date: 2023-02-22 DOI:10.1177/15347346231158175

Yun-Nan Lin, Yu-Chi Wang, Su-Shin Lee, Meng-Chien Willie Hsieh, Sin-Daw Lin, Shu-Hung Huang, Tsai-Ming Lin, Yur-Ren Kuo

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Abstract

Skin avulsion wounds are expected to be swollen and tense after trauma, and skin perfusion can be compromised after primary closure, resulting in wound dehiscence and poor healing. The artificial dermis (AD) serves as a dermal regeneration template that is used to heal skin defects with secondary intention. Therefore, the aim of this study is to evaluate the effect of AD application on traumatic skin avulsion injuries compared to conventional primary closure. A retrospective cohort of 20 patients with skin avulsion injuries were included the study: ten patients were treated with AD and ten patients were managed with primary closure. When compared to the primary closure group, AD group had a shorter average healing time (58.40 ± 26.94 days V 65.50 ± 46.45 days) and significantly higher flap viability (92.00 ± 13.17% V 78.00 ± 13.98%; p = .03). In conclusion, AD is a promising material for the treatment of skin avulsion injury and produces better clinical results.

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人造真皮对皮肤撕脱伤重建的桥接作用

皮肤撕脱伤在创伤后预计会肿胀和紧张，皮肤灌注会在一次闭合后受到影响，导致伤口开裂和愈合不良。人造真皮（AD）可作为真皮再生模板，用于二次意向性皮肤缺损愈合。因此，本研究旨在评估应用人工真皮对创伤性皮肤撕脱伤的效果，并与传统的一次闭合术进行比较。本研究对 20 名皮肤撕脱伤患者进行了回顾性队列分析，其中 10 名患者接受了 AD 治疗，10 名患者接受了一次闭合治疗。与初级闭合组相比，AD 组的平均愈合时间更短（58.40 ± 26.94 天 V 65.50 ± 46.45 天），皮瓣存活率显著更高（92.00 ± 13.17% V 78.00 ± 13.98%; p = .03）。总之，AD 是一种治疗皮肤撕脱伤的有前途的材料，能产生更好的临床效果。

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来源期刊

International Journal of Lower Extremity Wounds DERMATOLOGY-SURGERY

CiteScore

4.60

自引率

17.60%

发文量

审稿时长

>12 weeks

期刊介绍： The International Journal of Lower Extremity Wounds (IJLEW) is a quarterly, peer-reviewed journal publishing original research, reviews of evidence-based diagnostic techniques and methods, disease and patient management, and surgical and medical therapeutics for lower extremity wounds such as burns, stomas, ulcers, fistulas, and traumatic wounds. IJLEW also offers evaluations of assessment and monitoring tools, dressings, gels, cleansers, pressure management, footwear/orthotics, casting, and bioengineered skin. This journal is a member of the Committee on Publication Ethics (COPE).