Stress Hyperglycemia Ratio Is Associated With High Thrombus Burden in Patients With Acute Coronary Syndrome.

IF 2.6 3区医学 Q2 PERIPHERAL VASCULAR DISEASE

Angiology Pub Date : 2024-08-01 Epub Date: 2023-04-02 DOI:10.1177/00033197231167054

Engin Algül, Nail Burak Özbeyaz, Haluk Furkan Şahan, Faruk Aydınyılmaz, Hamza Sunman, Murat Tulmaç

{"title":"Stress Hyperglycemia Ratio Is Associated With High Thrombus Burden in Patients With Acute Coronary Syndrome.","authors":"Engin Algül, Nail Burak Özbeyaz, Haluk Furkan Şahan, Faruk Aydınyılmaz, Hamza Sunman, Murat Tulmaç","doi":"10.1177/00033197231167054","DOIUrl":null,"url":null,"abstract":"The blood glucose level at admission indicates (with some limitations) poor prognosis and thrombus burden in patients with the acute coronary syndrome (ACS). Our study aimed to measure the predictive value of the stress hyperglycemia ratio (SHR), an indicator of stress hyperglycemia, showing increased thrombus burden in patients with ACS. Patients (n = 1222) with ACS were enrolled in this cross-sectional study. Coronary thrombus burden was classified as high and low. SHR was calculated by dividing the admission serum glucose by the estimated average glucose derived from HbA1c. Low thrombus burden was detected in 771 patients, while high thrombus burden (HTB) was detected in 451 patients. SHR was found to be significantly higher in patients with HTB (1.1 ± .3 vs 1.06 ± .4; P = .002). SHR was determined as a predictor of HTB (odds ratio (OR) 1.547 95% CI (1.139-2.100), P < .001) as a result of univariate analysis. According to multivariate analysis, SHR was determined as an independent risk factor for HTB (OR 1.328 CI (1.082-1.752), P = .001). We found that SHR predicted thrombus burden with higher sensitivity than admission glucose level in patients with ACS.","PeriodicalId":8264,"journal":{"name":"Angiology","volume":" ","pages":"645-650"},"PeriodicalIF":2.6000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Angiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00033197231167054","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/4/2 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}

引用次数: 0

Abstract

The blood glucose level at admission indicates (with some limitations) poor prognosis and thrombus burden in patients with the acute coronary syndrome (ACS). Our study aimed to measure the predictive value of the stress hyperglycemia ratio (SHR), an indicator of stress hyperglycemia, showing increased thrombus burden in patients with ACS. Patients (n = 1222) with ACS were enrolled in this cross-sectional study. Coronary thrombus burden was classified as high and low. SHR was calculated by dividing the admission serum glucose by the estimated average glucose derived from HbA1c. Low thrombus burden was detected in 771 patients, while high thrombus burden (HTB) was detected in 451 patients. SHR was found to be significantly higher in patients with HTB (1.1 ± .3 vs 1.06 ± .4; P = .002). SHR was determined as a predictor of HTB (odds ratio (OR) 1.547 95% CI (1.139-2.100), P < .001) as a result of univariate analysis. According to multivariate analysis, SHR was determined as an independent risk factor for HTB (OR 1.328 CI (1.082-1.752), P = .001). We found that SHR predicted thrombus burden with higher sensitivity than admission glucose level in patients with ACS.

查看原文本刊更多论文

应激性高血糖比率与急性冠状动脉综合征患者的高血栓负荷有关。

入院时的血糖水平预示着急性冠状动脉综合征（ACS）患者的不良预后和血栓负荷（有一定的局限性）。我们的研究旨在测量应激性高血糖比值（SHR）的预测价值，它是应激性高血糖的一个指标，可显示急性冠状动脉综合征患者血栓负荷的增加。这项横断面研究招募了 1222 名 ACS 患者。冠状动脉血栓负担分为高和低。SHR的计算方法是将入院时的血清葡萄糖除以根据HbA1c得出的估计平均血糖值。在 771 例患者中发现了低血栓负荷，而在 451 例患者中发现了高血栓负荷（HTB）。结果发现，HTB 患者的 SHR 明显更高（1.1 ± .3 vs 1.06 ± .4；P = .002）。单变量分析结果显示，SHR 是高血压的预测因子（几率比 (OR) 1.547 95% CI (1.139-2.100)，P < .001）。根据多变量分析，SHR 被确定为 HTB 的独立危险因素（OR 1.328 CI (1.082-1.752)，P = .001）。我们发现，在 ACS 患者中，SHR 预测血栓负荷的灵敏度高于入院时的血糖水平。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Angiology 医学-外周血管病

CiteScore

5.50

自引率

14.30%

发文量

180

审稿时长

6-12 weeks

期刊介绍： A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days