Intramolecular Click Cycloaddition Reactions: Synthesis of 1,2,3-Triazoles.

IF 1.7 4区化学 Q3 CHEMISTRY, ORGANIC

Current organic synthesis Pub Date : 2024-01-01 DOI:10.2174/1570179420666230407103320

Zahra Tashrifi, Mohammad Mohammadi Khanaposhtani, Saeed Bahadorikhalili, Bagher Larijani, Mohammad Mahdavi

引用次数: 0

Abstract

Click Chemistry, as a powerful tool, has been used for the synthesis of a variety of 1,2,3-triazoles. Among click cycloaddition reactions, intramolecular click reactions carried out in azido-alkyne precursors has not been thoroughly reviewed. Hence, in this review, we have summarized and categorised the recent literature (from 2012 on) based on the azidoalkynyl precursor's type and a brief and concise description of the involved mechanisms is presented. Accordingly, we have classified the relevant literature into three categories: (1) substitution precursors (2) addition and (3) multi-component reaction (MCR) products.

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分子内咔嗒环加成反应:1,2,3-三唑的合成。

Click化学作为一种强大的工具，已被用于合成各种1,2,3-三唑。在咔嗒环加成反应中，叠氮-炔前体分子内咔嗒反应的研究尚未得到全面的评述。因此，在这篇综述中，我们根据叠氮烷基前体的类型对最近的文献(从2012年开始)进行了总结和分类，并简要介绍了所涉及的机制。据此，我们将相关文献分为三类:(1)取代前体(2)加成(3)多组分反应(MCR)产物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current organic synthesis 化学-有机化学

CiteScore

3.40

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Current Organic Synthesis publishes in-depth reviews, original research articles and letter/short communications on all areas of synthetic organic chemistry i.e. asymmetric synthesis, organometallic chemistry, novel synthetic approaches to complex organic molecules, carbohydrates, polymers, protein chemistry, DNA chemistry, supramolecular chemistry, molecular recognition and new synthetic methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by experts who are internationally known for their eminent research contributions. The journal is essential reading to all synthetic organic chemists. Current Organic Synthesis should prove to be of great interest to synthetic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic synthesis.