Cochlear Health and Cochlear-implant Function.

IF 2.4 3区 医学 Q3 NEUROSCIENCES
Kara C Schvartz-Leyzac, Deborah J Colesa, Donald L Swiderski, Yehoash Raphael, Bryan E Pfingst
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引用次数: 0

Abstract

The cochlear implant (CI) is widely considered to be one of the most innovative and successful neuroprosthetic treatments developed to date. Although outcomes vary, CIs are able to effectively improve hearing in nearly all recipients and can substantially improve speech understanding and quality of life for patients with significant hearing loss. A wealth of research has focused on underlying factors that contribute to success with a CI, and recent evidence suggests that the overall health of the cochlea could potentially play a larger role than previously recognized. This article defines and reviews attributes of cochlear health and describes procedures to evaluate cochlear health in humans and animal models in order to examine the effects of cochlear health on performance with a CI. Lastly, we describe how future biologic approaches can be used to preserve and/or enhance cochlear health in order to maximize performance for individual CI recipients.

Abstract Image

耳蜗健康和人工耳蜗功能。
人工耳蜗(CI)被广泛认为是迄今为止开发的最具创新性和最成功的神经假体治疗方法之一。尽管结果各不相同,但CI能够有效改善几乎所有受试者的听力,并能显著改善严重听力损失患者的言语理解和生活质量。大量研究集中在有助于CI成功的潜在因素上,最近的证据表明,耳蜗的整体健康可能比以前认识到的发挥更大的作用。本文定义并回顾了耳蜗健康的属性,并描述了在人类和动物模型中评估耳蜗健康的程序,以检查耳蜗健康对CI表现的影响。最后,我们描述了如何使用未来的生物学方法来保护和/或增强耳蜗健康,以最大限度地提高个体CI接受者的表现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.10
自引率
12.50%
发文量
57
审稿时长
6-12 weeks
期刊介绍: JARO is a peer-reviewed journal that publishes research findings from disciplines related to otolaryngology and communications sciences, including hearing, balance, speech and voice. JARO welcomes submissions describing experimental research that investigates the mechanisms underlying problems of basic and/or clinical significance. Authors are encouraged to familiarize themselves with the kinds of papers carried by JARO by looking at past issues. Clinical case studies and pharmaceutical screens are not likely to be considered unless they reveal underlying mechanisms. Methods papers are not encouraged unless they include significant new findings as well. Reviews will be published at the discretion of the editorial board; consult the editor-in-chief before submitting.
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