Relation Between the Negative Cognitive Triad, Perceived Everyday Discrimination, Depressive Symptoms, and TNF-⍺ in Adolescents.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
ACS Applied Bio Materials Pub Date : 2024-12-01 Epub Date: 2023-04-03 DOI:10.1007/s10578-023-01530-z
Ashley Ann Dondanville, Patrick Pössel, G Rafael Fernandez-Botran
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引用次数: 0

Abstract

Our study is guided by Beck's cognitive stress-vulnerability model of depression. We examined the associations between perceived everyday discrimination (PED) and TNF-⍺, an inflammatory biomarker associated with risk for severe illness, through the negative cognitive triad (NCT; negative thoughts about the self, world, and future) and depressive symptoms in adolescents. We utilized a sample of 99 adolescents (36.4% female; ages 13-16, M = 14.10, SD = 0.52) in our cross-sectional study. We used PROCESS and AMOS to compute regressions and direct, indirect, and total effects of PED, NCT aspects and depressive symptoms on TNF-⍺. Negative views of the self and world mediated between PED and depressive symptoms and that negative views of the self and future mediated between PED and TNF-⍺. In conclusion, Beck's theory can be expanded to physical health providing directions for addressing mental and physical health simultaneously by restructuring adolescents' negative view of the self.

青少年消极认知三要素、感知到的日常歧视、抑郁症状和 TNF-⍺ 之间的关系。
我们的研究以贝克的抑郁症认知压力-脆弱性模型为指导。我们通过青少年的消极认知三要素(NCT;对自我、世界和未来的消极想法)和抑郁症状,研究了感知到的日常歧视(PED)和TNF-⍺(一种与严重疾病风险相关的炎症性生物标志物)之间的关联。我们在横断面研究中使用了 99 个青少年样本(36.4% 为女性;13-16 岁,M = 14.10,SD = 0.52)。我们使用 PROCESS 和 AMOS 计算了 PED、NCT 方面和抑郁症状对 TNF-⍺ 的回归和直接、间接及总效应。对自我和世界的消极看法在 PED 和抑郁症状之间起中介作用,对自我和未来的消极看法在 PED 和 TNF-⍺ 之间起中介作用。总之,贝克的理论可以扩展到身体健康领域,通过调整青少年对自我的消极看法,为同时解决心理和身体健康问题提供了方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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