Treatment paradigms in Parkinson's Disease and Covid-19.

3区 医学 Q2 Medicine
Iro Boura, Lucia Batzu, Espen Dietrichs, Kallol Ray Chaudhuri
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引用次数: 1

Abstract

People with Parkinson's Disease (PwP) may be at higher risk for complications from the Coronavirus Disease 2019 (Covid-19) due to older age and to the multi-faceted nature of Parkinson's Disease (PD) per se, presenting with a variety of motor and non-motor symptoms. Those on advanced therapies may be particularly vulnerable. Taking the above into consideration, along with the potential multi-systemic impact of Covid-19 on affected patients and the complications of hospitalization, we are providing an evidence-based guidance to ensure a high standard of care for PwP affected by Covid-19 with varying severity of the condition. Adherence to the dopaminergic medication of PwP, without abrupt modifications in dosage and frequency, is of utmost importance, while potential interactions with newly introduced drugs should always be considered. Treating physicians should be cautious to acknowledge and timely address any potential complications, while consultation by a neurologist, preferably with special knowledge on movement disorders, is advised for patients admitted in non-neurological wards. Non-pharmacological approaches, including the patient's mobilization, falls prevention, good sleep hygiene, emotional support, and adequate nutritional and fluid intake, are essential and the role of telemedicine services should be strengthened and encouraged.

Abstract Image

帕金森病和Covid-19的治疗模式。
由于年龄较大和帕金森病本身的多面性,帕金森病(PwP)患者患2019冠状病毒病(Covid-19)并发症的风险可能更高,帕金森病(PD)本身会出现各种运动和非运动症状。那些接受先进治疗的人可能特别容易受到伤害。考虑到上述因素,以及Covid-19对受影响患者的潜在多系统影响和住院并发症,我们正在提供基于证据的指导,以确保对受Covid-19影响的不同严重程度的PwP提供高标准的护理。在不突然改变剂量和频率的情况下,坚持多巴胺能药物治疗是至关重要的,同时应始终考虑与新引入药物的潜在相互作用。治疗医生应谨慎确认并及时处理任何潜在的并发症,而建议非神经病房的患者咨询神经学家,最好是具有运动障碍专业知识的人。非药物方法,包括患者的活动、预防跌倒、良好的睡眠卫生、情感支持以及充足的营养和液体摄入,都是必不可少的,应加强和鼓励远程医疗服务的作用。
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来源期刊
CiteScore
5.90
自引率
0.00%
发文量
75
审稿时长
>12 weeks
期刊介绍: Published since 1959, International Review of Neurobiology is a well-established series appealing to neuroscientists, clinicians, psychologists, physiologists and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.
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