COVID-19 immune response in adults post Measles-Rubella vaccination

Q3 Medicine

Vacunas Pub Date : 2023-10-01 DOI:10.1016/j.vacun.2023.05.004

Suwoyo Suwoyo, Erna Rahma Yani, Koekoeh Hardjito

{"title":"COVID-19 immune response in adults post Measles-Rubella vaccination","authors":"Suwoyo Suwoyo, Erna Rahma Yani, Koekoeh Hardjito","doi":"10.1016/j.vacun.2023.05.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to see how measles, mumps, and rubella vaccination affected the increase in SARS-CoV-2 immunoglobulin levels in individuals who had received the second dose of the SARS-CoV-2 vaccine.</p></div><div><h3>Material and method</h3><p>This research is a quasi-experimental type with a pre-post test design. The population studied were adults who had received the second dose of the SARS-CoV-2 vaccine, consisting of 30 people.</p></div><div><h3>Results</h3><p>The results of this study were that most (60%) research subjects experienced an increase in IgM and some subjects (46.6%) experienced an increase in anti-SARS-CoV-2 IgG levels. The administration of the MR vaccination had no effect on increasing anti-SARS-CoV-2 IgG and IgM levels. This happened because the increase in IgM and IgG levels in the pre and post-tests in most research subjects was relatively low.</p></div><div><h3>Conclusion</h3><p>The administration of the MR vaccine to adults who had received a second dose of the SARS-CoV-2 vaccine elicited a response with low levels of IgG and IgM SARS-CoV-2.</p></div>","PeriodicalId":53407,"journal":{"name":"Vacunas","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1576988723000365/pdfft?md5=b76809598cf6e41e652ab0d7bc117b12&pid=1-s2.0-S1576988723000365-main.pdf","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vacunas","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1576988723000365","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 1

Abstract

Objective

This study aimed to see how measles, mumps, and rubella vaccination affected the increase in SARS-CoV-2 immunoglobulin levels in individuals who had received the second dose of the SARS-CoV-2 vaccine.

Material and method

This research is a quasi-experimental type with a pre-post test design. The population studied were adults who had received the second dose of the SARS-CoV-2 vaccine, consisting of 30 people.

Results

The results of this study were that most (60%) research subjects experienced an increase in IgM and some subjects (46.6%) experienced an increase in anti-SARS-CoV-2 IgG levels. The administration of the MR vaccination had no effect on increasing anti-SARS-CoV-2 IgG and IgM levels. This happened because the increase in IgM and IgG levels in the pre and post-tests in most research subjects was relatively low.

Conclusion

The administration of the MR vaccine to adults who had received a second dose of the SARS-CoV-2 vaccine elicited a response with low levels of IgG and IgM SARS-CoV-2.

查看原文本刊更多论文

成人麻疹-风疹疫苗接种后的COVID-19免疫反应

目的本研究旨在了解麻疹、腮腺炎和风疹疫苗接种如何影响接受第二剂SARS-CoV-2疫苗的个体中SARS-CoV-2免疫球蛋白水平的增加。材料与方法本研究为准实验型，采用前后试验设计。研究的人群是接受了第二剂SARS-CoV-2疫苗的成年人，由30人组成。结果大多数(60%)研究对象IgM水平升高，部分(46.6%)研究对象抗sars - cov -2 IgG水平升高。MR疫苗接种对增加抗sars - cov -2 IgG和IgM水平没有影响。这是因为大多数研究对象在测试前后IgM和IgG水平的增加相对较低。结论接种过第二剂SARS-CoV-2疫苗的成人接种MR疫苗可引起低水平的SARS-CoV-2 IgG和IgM的应答。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Vacunas Medicine-Infectious Diseases

CiteScore

3.90

自引率

0.00%

发文量

138

审稿时长

62 days

期刊介绍： Sin duda una de las mejores publicaciones para conocer los avances en el campo de las vacunaciones preventivas, tanto en el ámbito de la investigación básica como aplicada y en la evaluación de programas de vacunaciones. Su alta calidad y utilidad la ha llevado a estar indexada en los prestigiosos índices IME y SCOPUS.