{"title":"Crocin-loaded nanocarriers; approaches and applications","authors":"Sedighe Tavasoli , Zahra Borjizadeh , Amirali Anvar , Hamed Ahari , Sima Moradi , Seid Mahdi Jafari","doi":"10.1016/j.cofs.2023.101099","DOIUrl":null,"url":null,"abstract":"<div><p>Crocin (CR), an important carotenoid in saffron, is known for its significant biological benefits. Despite its therapeutic potential, there are some challenges that hamper its use as an effective functional agent. These include limited absorption, low bioavailability, and inadequate stability. Nanodelivery systems are useful in addressing these obstacles and enhancing CR effectiveness through various mechanisms. This review aims to provide a recent overview of the research advancements in CR-loaded nanocarriers and to explore their potential benefits in food and pharma applications. Various research studies have been conducted on different nanocarriers for the delivery of CR, and their findings suggest that optimal encapsulation can improve the stability of CR, thereby preserving its therapeutic potency. Hence, nanocarriers show great promise as a means to develop nutraceuticals with enhanced bioavailability and efficacy.</p></div>","PeriodicalId":54291,"journal":{"name":"Current Opinion in Food Science","volume":"54 ","pages":"Article 101099"},"PeriodicalIF":8.9000,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Food Science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214799323001145","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FOOD SCIENCE & TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Crocin (CR), an important carotenoid in saffron, is known for its significant biological benefits. Despite its therapeutic potential, there are some challenges that hamper its use as an effective functional agent. These include limited absorption, low bioavailability, and inadequate stability. Nanodelivery systems are useful in addressing these obstacles and enhancing CR effectiveness through various mechanisms. This review aims to provide a recent overview of the research advancements in CR-loaded nanocarriers and to explore their potential benefits in food and pharma applications. Various research studies have been conducted on different nanocarriers for the delivery of CR, and their findings suggest that optimal encapsulation can improve the stability of CR, thereby preserving its therapeutic potency. Hence, nanocarriers show great promise as a means to develop nutraceuticals with enhanced bioavailability and efficacy.
期刊介绍:
Current Opinion in Food Science specifically provides expert views on current advances in food science in a clear and readable format. It also evaluates the most noteworthy papers from original publications, annotated by experts.
Key Features:
Expert Views on Current Advances: Clear and readable insights from experts in the field regarding current advances in food science.
Evaluation of Noteworthy Papers: Annotated evaluations of the most interesting papers from the extensive array of original publications.
Themed Sections: The subject of food science is divided into themed sections, each reviewed once a year.