Insuffisance antéhypophysaire

Abstract

Multiple signals from central nervous system and peripheral endocrine glands reach the hypothalamic-pituitary system which in turn controls hormonal secretions. Organic lesions or functional disorders of the hypothalamus and/or pituitary lead to a more or less rapid, marked, or complete functional failure of their target endocrine tissues, which consequently induces a pattern of clinical and biological signs. The identification of both a pituitary deficiency and its cause is a prerequisite to the choice of the therapeutic approach. This stage of the diagnosis needs hormonal and radiological investigations which finally will allow determining the endocrine dysfunction pathogenesis.