Membrane fusion boosting drug transmembrane delivery

Abstract

Benefiting from fusion element (peptides or proteins) anchoring, several biological membrane vesicles or synthetic liposomes have great potency to fuse with the target cell membrane via virus-mimetic behavior. When this process happens, the encapsulated cargos can be released directly into the cytoplasm together with membrane component (protein receptor, channel proteins, chemical receptors, antibodies) transfer, a process that facilitates cellular/molecular diagnosis and therapy.