A postmortem study of patients vaccinated for SARS-CoV-2 in Colombia

Q4 Medicine
Juan José Chaves , Juan Carlos Bonilla , Viviana Chaves-Cabezas , Andrés Castro , José Fernando Polo , Oscar Mendoza , Jennifer Correa-Rodríguez , Ana Carolina Piedrahita , Ivan Alberto Romero-Fandiño , María Victoria Caro , Andrea Carolina González , Lisseth Katherine Sánchez , Félix Murcia , Gloria Márquez , Alejandra Benavides , María del Pilar Quiroga , Jorge López , Rafael Parra-Medina
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引用次数: 1

Abstract

Introduction and objective

A new coronavirus produces a disease designated as coronavirus disease 2019 (COVID-19). Vaccination against COVID-19 has resulted in decreased mortality. Postmortems of vaccinated patients play an important part in the forensic analysis of adverse effects after vaccination, which is essential for determining its efficacy and security. The main objective of this study was to describe the results of autopsies of patients vaccinated for SARS-CoV-2 carried out in two major centers in Colombia.

Materials and methods

A descriptive cross-sectional study of 121 autopsies was performed following Colombian regulations in two main hospitals in Bogotá, Colombia, between March 1st and April 31st, 2021.

Results

118 of the 121 patients (97.52%) had been vaccinated with CoronaVac (Sinovac); only 3 had received other vaccines. Sudden cardiac death was the leading cause of death, with pulmonary embolism another critical finding. No relation between the cause of death and vaccination against SARS-CoV-2 was found.

Conclusions

A clinical autopsy is a vital for an accurate post-mortem diagnosis. Any relation between the SARS-CoV-2 vaccine and the cause of death should be carefully studied in order to provide the general public with evidence-based information about the safety of the vaccination.

哥伦比亚SARS-CoV-2疫苗接种患者的尸检研究
简介与目的新型冠状病毒产生一种被命名为2019冠状病毒病(新冠肺炎)的疾病。接种新冠肺炎疫苗已降低死亡率。接种疫苗后患者的尸检在疫苗接种后不良反应的法医学分析中起着重要作用,这对确定疫苗的有效性和安全性至关重要。本研究的主要目的是描述在哥伦比亚两个主要中心对接种严重急性呼吸系统综合征冠状病毒2型疫苗的患者进行尸检的结果。材料和方法根据哥伦比亚法规,于3月1日至4月31日在哥伦比亚波哥大的两个主要医院对121例尸检进行了描述性横断面研究,2021.结果121例患者中118例(97.52%)接种了科兴疫苗;只有3人接种了其他疫苗。心源性猝死是死亡的主要原因,肺栓塞是另一个重要发现。没有发现死亡原因与接种严重急性呼吸系统综合征冠状病毒2型疫苗之间的关系。结论临床尸检对准确的尸检诊断至关重要。应仔细研究严重急性呼吸系统综合征冠状病毒2型疫苗与死亡原因之间的任何关系,以便向公众提供有关疫苗安全性的循证信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Revista Espanola de Patologia
Revista Espanola de Patologia Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
53
审稿时长
34 days
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