Post-COVID-19 respiratory problems: burden and management.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2022-12-01 DOI:10.1097/SPC.0000000000000619

Anna Kessler, Melissa Heightman, Ewen Brennan

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引用次数: 1

Abstract

Purpose of review: To describe the burden of post-COVID respiratory sequelae in posthospital and nonhospitalized COVID-19 survivors and to describe the priorities of clinical management.

Recent findings: Due to varying definitions of 'Long COVID' or 'Post-COVID', the prevalence of post-COVID sequelae or persisting symptoms is challenging to estimate but ranges from 2.3 to 51%. Risk factors for persistent post-COVID symptoms include age, female sex, deprivation, presence of comorbidities; and in posthospital COVID-19 survivors, the severity of acute infection. Common post-COVID respiratory symptoms include breathlessness, cough and chest pain and many individuals also experience exercise intolerance. The most common pulmonary function test abnormality is impaired diffusing capacity for carbon monoxide. In posthospital COVID-19 survivors, the prevalence of interstitial lung damage is 5-11%. Disordered breathing is common in all post-COVID patients and respiratory physiotherapy is helpful.

Summary: The vast numbers of COVID-19 infections globally implies that a large number of people will be affected by post-COVID sequelae even with conservative estimates. A significant number of people are affected for several months and up to years following acute infection. Post-COVID sequelae have a detrimental impact on quality of life and ability to work.

查看原文本刊更多论文

covid -19后呼吸道问题:负担和管理。

综述目的:了解2019冠状病毒病住院后和非住院幸存者的肺炎后呼吸后遗症负担情况，并探讨临床处理的重点。由于“长COVID”或“后COVID”的定义不同，COVID后后遗症或持续症状的患病率难以估计，但范围从2.3到51%。持续出现covid后症状的危险因素包括年龄、女性、贫困、存在合并症;在COVID-19住院后幸存者中，急性感染的严重程度。常见的新冠肺炎后呼吸道症状包括呼吸困难、咳嗽和胸痛，许多人还会出现运动不耐症。最常见的肺功能检查异常是一氧化碳扩散能力受损。在COVID-19住院后幸存者中，间质性肺损伤的发生率为5-11%。呼吸障碍在所有covid后患者中都很常见，呼吸物理治疗是有帮助的。总结:全球COVID-19感染人数众多，这意味着即使保守估计，仍有大量人口将受到COVID-19后后遗症的影响。相当多的人在急性感染后会受到几个月甚至几年的影响。covid后后遗症对生活质量和工作能力产生不利影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.