Clinicopathological Features of Cutaneous Findings of SARS-CoV-2 Infection.

IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL
Bengu Cobanoglu, Filiz Cebeci, Mustafa Simsek, Seyma Ozkanli
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引用次数: 0

Abstract

Objective: In December 2019, severe acute respiratory syndrome coronavirus-2, which emerged in Wuhan, China, spread rapidly and created a pandemic. Coronavirus disease-2019 (COVID-19) can affect different organ systems, including the skin. Recently, COVID-19 cases with skin lesions of different clinicopathological features have been published. This study aimed to present the histopathological features of 19 COVID-19 cases with cutaneous findings and discuss them in light of the literature.

Methods: Skin biopsy specimens of 19 patients with skin rashes associated with COVID-19 were evaluated histopathologically and clinically.

Results: Clinical manifestations of rashes developed in eight female, seven male, and four pediatric patients with COVID-19. Urticaria/urticarial vasculitis (n=7), maculopapular eruption (n=7), panniculitis (n=2), purpuric eruptions (n=2), and livedoid-like lesions were noted. Histopathologically, besides the inflammatory findings, the most striking feature was that the vessels were more or less affected in almost all cases.

Conclusions: Cutaneous lesions associated with COVID-19 are increasingly being reported. We believe that every data presented about this disease, which has many unknowns, will shed light on future research. Every case can lead us a new way.

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SARS-CoV-2 感染皮肤症状的临床病理特征
目的:2019年12月,在中国武汉出现的严重急性呼吸综合征冠状病毒-2迅速传播并造成大流行。冠状病毒病-2019(COVID-19)可影响包括皮肤在内的不同器官系统。最近,发表了一些具有不同临床病理特征的皮肤病变的 COVID-19 病例。本研究旨在介绍19例COVID-19皮肤病变病例的组织病理学特征,并结合文献进行讨论:对19例与COVID-19相关的皮疹患者的皮肤活检标本进行了组织病理学和临床评估:8名女性、7名男性和4名儿童COVID-19患者出现皮疹的临床表现。荨麻疹/荨麻疹性血管炎(7 例)、斑丘疹(7 例)、泛发性皮炎(2 例)、紫癜性皮疹(2 例)和类鳞状皮损。从组织病理学角度看,除了炎症发现外,最显著的特征是几乎所有病例的血管都或多或少受到影响:结论:与 COVID-19 相关的皮肤病变报道越来越多。我们相信,关于这种存在许多未知因素的疾病的每一个数据都将为未来的研究带来启示。每一个病例都能为我们指引一条新的道路。
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来源期刊
Medeniyet medical journal
Medeniyet medical journal Medicine-Medicine (all)
CiteScore
1.70
自引率
0.00%
发文量
88
审稿时长
5 weeks
期刊介绍: The Medeniyet Medical Journal (Medeniyet Med J) is an open access, peer-reviewed, and scientific journal of Istanbul Medeniyet University Faculty of Medicine on various academic disciplines in medicine, which is published in English four times a year, in March, June, September, and December by a group of academics. Medeniyet Medical Journal is the continuation of Göztepe Medical Journal (ISSN: 1300-526X) which was started publishing in 1985. It changed the name as Medeniyet Medical Journal in 2015. Submission and publication are free of charge. No fees are asked from the authors for evaluation or publication process. All published articles are available online in the journal website (www.medeniyetmedicaljournal.org) without any fee. The journal publishes intradisciplinary or interdisciplinary clinical, experimental, and basic researches as well as original case reports, reviews, invited reviews, or letters to the editor, Being published since 1985, the Medeniyet Med J recognizes that the best science should lead to better lives based on the fact that the medicine should serve to the needs of society, and knowledge should transform society. The journal aims to address current issues at both national and international levels, start debates, and exert an influence on decision-makers all over the world by integrating science in everyday life. Medeniyet Med J is committed to serve the public and influence people’s lives in a positive way by making science widely accessible. Believing that the only goal is improving lives, and research has an impact on people’s lives, we select the best research papers in line with this goal.
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