Prevalence of asymptomatic SARS-CoV-2 infection in an Austrian cohort

Clinical Immunology Communications Pub Date : 2021-12-01 DOI:10.1016/j.clicom.2021.08.002

Elisabeth Mara, Verena Breitsching, Tanja Schuster, Thomas Pekar

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引用次数: 2

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged at the end of 2019, causing the coronavirus disease (COVID-19). The main sources of infections are infected and asymptomatic persons. One major problem of the pandemic are the diverse symptoms and the varying manifestations of the illness. In this study, the IgG level recognizing the RBD of SARS-CoV-2 was determined within 336 volunteers from the environment of the University of Applied Sciences Wiener Neustadt. The aims of this study were to identify the estimated number of undiscovered COVID-19 infections and the corresponding antibody levels. In total, 11.3% of the nonvaccinated probands had a positive IgG antibody titer against SARS-CoV-2, whereas 4.0% did not test positive for SARS-CoV-2 or had never been tested at the time of sampling. Probands in this study reported tiredness (57,5%), ageusia/anosmia (55%) and headache (47,5%) as most frequent symptoms.

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奥地利人群中无症状SARS-CoV-2感染的流行情况

严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)于2019年底首次出现，引起冠状病毒病(COVID-19)。感染的主要来源是感染者和无症状者。该流行病的一个主要问题是该疾病的各种症状和各种表现。在本研究中，我们检测了来自维也纳新城应用科学大学的336名志愿者中识别SARS-CoV-2 RBD的IgG水平。本研究的目的是确定未发现的COVID-19感染的估计数量和相应的抗体水平。总体而言，11.3%未接种疫苗的先证者具有针对SARS-CoV-2的IgG抗体滴度阳性，而4.0%未检测出SARS-CoV-2阳性或在采样时从未检测过。在这项研究中，先证者报告疲倦(57.5%)、老年/嗅觉丧失(55%)和头痛(47.5%)是最常见的症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Clinical Immunology Communications

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