An unequivocal determination of heroin in simulated street drugs by a combination of high-performance liquid chromatography and infrared spectrophotometry using micro-sampling techniques

Abstract

An unequivocal determination of heroin in simulated street samples is deseribed. Heroin is separated from the active excipients and contaminants by reverse-phase high-performance liquid chromatography. An infrared spectrum is obtained using semimicro-sampling techniques on the heroin fraction collected. The total analysis time is 50 minutes.