Kinetics of the in vivo31P1H nuclear overhauser effect of the human-calf-muscle phosphocreatine resonance

Journal of Magnetic Resonance (1969) Pub Date : 1992-10-15 DOI:10.1016/0022-2364(92)90372-E

Peter Bachert, Matthias E Bellemann

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引用次数: 21

Abstract

In ³¹P¹H double-resonance experiments in a 1.5 T whole-body MR system, we observed in vivo the truncated driven, transient, and steady-state ³¹P-¹H nuclear Overhauser effect of the phosphocreatine resonance in ³¹P MR spectra of human gastrocnemius muscle. Maximum signal enhancements of 0.52 ± 0.01, 0.20 ± 0.01, and 0.79 ± 0.02 were measured, respectively. Fitting the data with theoretical functions which solve the multispin Solomon equations for N protons (S spins) dipolar coupled to a ³¹P nucleus (I spin) yields cross-relaxation times $2 [Σ_{i=1−N^{σ}IS(i)}]$ in the order of 20 s. In vivo experiments are feasible for studying relaxation mechanisms in coupled ³¹P¹H spin systems in intact tissue.

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人-小腿肌磷酸肌酸共振的体内31p1H核大修效应动力学

在1.5 T全身MR系统的31P1H双共振实验中，我们在体内观察了人腓肠肌31P MR光谱中磷酸肌酸共振的截断驱动、瞬态和稳态31P-1H核Overhauser效应。最大信号增强分别为0.52±0.01、0.20±0.01和0.79±0.02。用求解N个质子(S自旋)偶极子耦合到31P核(I自旋)的多自旋所罗门方程的理论函数拟合数据得到交叉弛豫时间2[Σi=1−N σIS(I)]，其数量级为20 S。完整组织中耦合31P1H自旋体系的弛豫机制的体内实验研究是可行的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of Magnetic Resonance (1969)

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