A γ-globulin glycoprotein in bovine vitreous body

Abstract

A glycoprotein containing 4.3% neutral sugar, 2.07% amino sugar and 0.4% sialic acid has been isolated from bovine vitreous body. It is electrophoretically homogeneous and has a mobility of −2.2·10⁻⁵ cm²/V sec, which places it among the γ-globulins. The sedimentation coefficient and diffusion constant indicate a molecular weight slightly lower than the generally accepted values for γ-globulins. Other examples of connective tissue proteins which resemble, but are not identical to, plasma proteins are discussed.