Medical transition for gender diverse patients.

IF 0.7 Q4 OBSTETRICS & GYNECOLOGY

Current Obstetrics and Gynecology Reports Pub Date : 2020-12-01 DOI:10.1007/s13669-020-00297-7

Chelsea N Fortin, Molly B Moravek

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Abstract

Purpose of review: The purpose of this review is to provide an up-to-date overview of gender-affirming hormone therapy, including the various hormone regimens available, the efficacy and potential risks of these treatments, and considerations for surveillance and long-term care.

Recent findings: Recent studies reaffirm that hormone therapy has positive physical and psychological effects for many transgender individuals. The overall risks of treatment are low. Transgender women may have an increased risk of venous thromboembolism and breast cancer based on recent cohort studies, but these findings have yet to be confirmed with randomized controlled trials. Important long-term considerations include metabolic, cardiovascular, and skeletal health.

Summary: High-quality, long-term studies on the effectiveness and safety of various gender-affirming hormone treatment regimens are lacking, but the currently available evidence suggests that it is overall safe and effective with appropriate oversight.

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性别差异患者的医疗转变。

综述的目的:本综述的目的是提供性别肯定激素治疗的最新概况，包括各种可用的激素治疗方案，这些治疗的疗效和潜在风险，以及对监测和长期护理的考虑。最近的发现:最近的研究重申，激素治疗对许多变性人有积极的生理和心理影响。治疗的总体风险很低。根据最近的队列研究，变性女性患静脉血栓栓塞和乳腺癌的风险可能增加，但这些发现尚未得到随机对照试验的证实。重要的长期考虑包括代谢、心血管和骨骼健康。摘要:目前缺乏对各种性别肯定激素治疗方案的有效性和安全性的高质量、长期研究，但目前可获得的证据表明，在适当的监督下，它总体上是安全有效的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Obstetrics and Gynecology Reports OBSTETRICS & GYNECOLOGY-

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期刊介绍： This journal aims to provide expert review articles on significant recent developments in obstetrics and gynecology. Presented in clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the diagnosis, treatment, management, and prevention of conditions that compromise the health of women. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as endometriosis, infertility, menopause, prenatal medicine, and vulval and cervical lesions. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An Editorial Board of nearly 20 international members reviews the annual table of contents, suggests articles of special importance to their country/region, and ensures that topics include emerging research. Commentaries from well-known figures in the field are also provided.