“Clinical Profile & Prognostic Factors In Patients with Sudden Sensorineural Hearing Loss”

Md. Feroz Hossen, Mahbubul Alam Choudhury
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Abstract

Introduction: Idiopathic sudden sensorineural hearing loss (ISSNHL) is an emergency disease requiring immediate diagnosis and treatment. The incidence of ISSNHL in the Western countries’ population was estimated to 5–20 per 100,000 inhabitants. The etiology of ISSNHL remains unknown. Its pathogenesis is most often suggested to be due to a disturbed microcirculation and infection. Objective: To study the clinical profile & prognostic factors in patients with sudden sensorineural hearing loss. Material and Methods: A retrospective study was carried out from patients of sudden sensineural hearing loss (SSNHL) presenting to ENT Department ofNorthern Private Medical College, Rangpur, Bangladesh from January to June-2020. All patients were given intravenous steroids as treatment modality for 14 days and pure tone audiogram was done every 3 days during hospital admission. It was followed by oral steroids in tapering dose for further 14 days. After 1 month, audiogram was done again. After 1 month if hearing threshold was decreased by more than 50% of presenting one, then it was labeled as improved. Results:Total 51 patients (55ears) with age ranging from 6-70 years (average-38.5 years) were included. Three fourth were male. Presentation was 1-14days after onset of hearing loss (average- 3.7days) with pure tone audiogram (PTA) of 38-117dB (average 83.1dB). The flat audiogram (62.3%) was most common type. Smoking was present in 14 patients and tinnitus in 30 ears. Hemoglobin ranged from 7.3-18.7gm %( average- 15.3gm/dl). PTA post treatment was 8-73dB (average- 56dB). Average age of improved patient was 39.8years which was lower than non-improved patients (42.3years). In improved patients, average PTA at presentation was 77.9dB while it was 86.6dB in non-improved patients. Conclusion: Our study demonstrates that the age distribution and clinical characteristics of ISSNHL patients vary according to levels of hearing loss. Moreover, ISSNHL patients with vertigo tend to sufer from a more severe hearing loss. Further studies are needed to obtain better knowledge about the etiopathogenesis of SSNHL.  SSNHL is more commonly seen in male patients with polycythaemia and is commonly presented in winter season and is frequently associated with tinnitus. Young age and lower audiogram threshold at presentation favor prognosis.
突发性感音神经性听力损失患者的临床特点及预后因素
简介:特发性突发性感音神经性听力损失(ISSNHL)是一种需要立即诊断和治疗的急症。在西方国家的人口中,ISSNHL的发病率估计为每10万居民5-20人。ISSNHL的病因尚不清楚。其发病机制常被认为是由于微循环紊乱和感染所致。目的:探讨突发性感音神经性听力损失的临床特点及影响预后的因素。材料和方法:对2020年1月至6月在孟加拉国Rangpur北部私立医学院耳鼻喉科就诊的突发性感音性听力损失(SSNHL)患者进行回顾性研究。所有患者均给予静脉注射类固醇治疗14 d,住院期间每3天做一次纯音听音图。随后口服类固醇,剂量逐渐减少,再持续14天。1个月后再次行听力图。1个月后,如果听力阈值下降超过50%,则标记为改善。结果:共纳入51例患者(55耳),年龄6 ~ 70岁,平均38.5岁。四分之三是男性。发病后1-14天(平均- 3.7天)出现,纯音听图(PTA) 38-117dB(平均83.1dB)。扁平型为最常见类型,占62.3%。吸烟14例,耳鸣30例。血红蛋白范围为7.3-18.7gm %(平均- 15.3gm/dl)。PTA处理后为8-73dB(平均- 56dB)。改善患者的平均年龄为39.8岁,低于未改善患者(42.3岁)。改善患者就诊时平均PTA为77.9dB,未改善患者为86.6dB。结论:我们的研究表明,ISSNHL患者的年龄分布和临床特征随听力损失程度的不同而不同。此外,伴有眩晕的ISSNHL患者往往会出现更严重的听力损失。为了更好地了解SSNHL的发病机制,还需要进一步的研究。SSNHL多见于男性红细胞增多症患者,常见于冬季,常伴有耳鸣。年轻和较低的听力学阈值有利于预后。
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