Experimental design for optimization of D-lactic acid production using a UV-light selected strain

Abstract

Lactic acid (LA) is an organic acid with a hydroxyl and an acid functional group.1,2 It can be produced by humans, plants, animals and microorganisms.2 It has an asymmetric carbon and it naturally occurs as two optical isomers, Dand L-LA, due to the existence of a chiral centre.1,3 It was discovered in 1780 by the experimental chemist Carl Wilhelm Scheele, isolated from sour milk. Currently is known as 2-hydroxypropanoic acid.4