Mohamed Bounouib, Hind Benakrach, Mourad Taha-Janan, Wajih Maazouzi
{"title":"Analysis of shear stress related hemolysis in a ventricular assist device.","authors":"Mohamed Bounouib, Hind Benakrach, Mourad Taha-Janan, Wajih Maazouzi","doi":"10.3233/BME-221401","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Implantable devices such as ventricular assist devices provide appropriate treatment for patients with advanced heart failure. Unfortunately, these devices still have many problems, particularly related to blood damage.</p><p><strong>Objective: </strong>The aim of this research is to examine two new ventricular assist devices in terms of induced shear stress, exposure time, and induced hemolysis.</p><p><strong>Method: </strong>Reverse engineering was used on multiple axial flow ventricular assist devices to collect all the details related to the designs (diameters, lengths, blade angles…), which were used to build two prototypes: Model A and Model B.</p><p><strong>Results: </strong>The obtained results were close to a large extent, except for static pressure rise, where the difference was clear.</p><p><strong>Conclusion: </strong>Compared with what has been published in other studies, the overall performance of both models was excellent.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":"34 1","pages":"51-66"},"PeriodicalIF":1.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bio-medical materials and engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3233/BME-221401","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Implantable devices such as ventricular assist devices provide appropriate treatment for patients with advanced heart failure. Unfortunately, these devices still have many problems, particularly related to blood damage.
Objective: The aim of this research is to examine two new ventricular assist devices in terms of induced shear stress, exposure time, and induced hemolysis.
Method: Reverse engineering was used on multiple axial flow ventricular assist devices to collect all the details related to the designs (diameters, lengths, blade angles…), which were used to build two prototypes: Model A and Model B.
Results: The obtained results were close to a large extent, except for static pressure rise, where the difference was clear.
Conclusion: Compared with what has been published in other studies, the overall performance of both models was excellent.
期刊介绍：
The aim of Bio-Medical Materials and Engineering is to promote the welfare of humans and to help them keep healthy. This international journal is an interdisciplinary journal that publishes original research papers, review articles and brief notes on materials and engineering for biological and medical systems. Articles in this peer-reviewed journal cover a wide range of topics, including, but not limited to: Engineering as applied to improving diagnosis, therapy, and prevention of disease and injury, and better substitutes for damaged or disabled human organs; Studies of biomaterial interactions with the human body, bio-compatibility, interfacial and interaction problems; Biomechanical behavior under biological and/or medical conditions; Mechanical and biological properties of membrane biomaterials; Cellular and tissue engineering, physiological, biophysical, biochemical bioengineering aspects; Implant failure fields and degradation of implants. Biomimetics engineering and materials including system analysis as supporter for aged people and as rehabilitation; Bioengineering and materials technology as applied to the decontamination against environmental problems; Biosensors, bioreactors, bioprocess instrumentation and control system; Application to food engineering; Standardization problems on biomaterials and related products; Assessment of reliability and safety of biomedical materials and man-machine systems; and Product liability of biomaterials and related products.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
