Initiation and adherence to isoniazid preventive therapy in children under 5 years of age in Manhiça, Southern Mozambique.

IF 1.8 4区医学 Q2 PEDIATRICS

Journal of Tropical Pediatrics Pub Date : 2022-12-05 DOI:10.1093/tropej/fmad009

Agnès Montoya I de Manuel-Rimbau, Dinis Nguenha, Edson Mambuque, Joanna Ehrlich, Shilzia Munguambe, Belén Saavedra, Teodimiro Matsena, Hélio Chiconela, Aina Casellas, Elisa López-Varela, Sozinho Acacio, Alberto L Garcia-Basteiro

引用次数: 0

Abstract

The WHO recommends preventive treatment for all pediatric contacts of a confirmed TB case, but coverage remains low in many high TB burden countries. We aimed to assess the coverage and adherence of the isoniazid preventive therapy (IPT) program among children under 5 years of age with household exposure to an adult pulmonary TB case in a rural district of Southern Mozambique. The estimated IPT coverage was 11.7%. A longer distance to the health center and lower age of the children hindered IPT initiation. Among patients who started IPT, 12/18 (69.9%) were adherent to the 6-month treatment.

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莫桑比克南部曼西帕拉5岁以下儿童开始和坚持异烟肼预防性治疗。

世卫组织建议对结核确诊病例的所有儿童接触者进行预防性治疗，但在许多结核病高负担国家，治疗覆盖率仍然很低。我们的目的是评估莫桑比克南部农村地区家庭暴露于成人肺结核病例的5岁以下儿童异烟肼预防治疗(IPT)计划的覆盖率和依从性。估计IPT覆盖率为11.7%。距离保健中心较远和儿童年龄较低阻碍了IPT的开始。在开始IPT的患者中，12/18(69.9%)的患者坚持6个月的治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Tropical Pediatrics 医学-热带医学

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal of Tropical Pediatrics provides a link between theory and practice in the field. Papers report key results of clinical and community research, and considerations of programme development. More general descriptive pieces are included when they have application to work preceeding elsewhere. The journal also presents review articles, book reviews and, occasionally, short monographs and selections of important papers delivered at relevant conferences.