Evaluation of the clinical efficacy of anti-inflammatory therapy with topical biclotymol-based products

Q4 Medicine

Otorhinolaryngology Clinics Pub Date : 2023-01-30 DOI:10.37219/2528-8253-2022-6-66

Julia V. Dieieva

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引用次数: 0

Abstract

Topicality: Acute pharyngeal diseases are one of the most common reasons for patients to visit a doctor. According to the UK, approximately 50% of these diseases account for the appointment of antibacterial agents. Most of these prescriptions are not rational, but doctors use them for several reasons - unreal expectations of treatment, patient pressure/insistence on conducting the desired tests or treatment, the doctor's desire to maintain a better doctor-patient relationship, limited consultation time, diagnostic uncertainty, incorrect collection of historical data and others. Despite these reasons, patients with acute pharyngitis and tonsillitis who seek antibiotic therapy want to reduce their symptoms. Therefore, the search for agents that will significantly improve patients' quality of life during acute pharyngeal diseases is crit ical. Aim: To review the literature on the therapeutic efficacy of topical biclotymol-based products for treating acute pharyngeal diseases. Results and discussion: Most cases of acute pharyngitis should be treated with over-the-counter medicines that are primarily intended to control the symptoms of the disease and improve the patient's quality of life. Biclotymol, enoxolone and lysozyme are novel substances that, at the same time, are safe for resolving pain in viral or bacterial pharyngit is. Biclotymol can be used as monotherapy and in combination with other agents. In the analysed data, biclotymol showed its therapeutic efficacy and safety. Therefore, it is safe to recommend biclotymolbased products for use in acute viral and bacterial pharyngitis or tonsillitis both as monocomponent medicine and fixed-dose combination.

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局部双小叶酮类产品抗炎治疗的临床疗效评价

话题性:急性咽部疾病是患者去看医生最常见的原因之一。据英国统计，这些疾病中约有50%需要使用抗菌剂。这些处方大多是不合理的，但医生使用它们有几个原因——对治疗的不切实际的期望，患者压力/坚持进行所需的检查或治疗，医生希望保持更好的医患关系，有限的咨询时间，诊断的不确定性，历史数据的不正确收集等等。尽管有这些原因，急性咽炎和扁桃体炎患者寻求抗生素治疗希望减轻症状。因此，寻找能够显著改善急性咽部疾病患者生活质量的药物至关重要。目的:综述以双小叶为基础的外用制剂治疗急性咽部疾病的临床疗效。结果和讨论:大多数急性咽炎病例应使用非处方药治疗，这些非处方药的主要目的是控制疾病的症状和改善患者的生活质量。双氯霉酚、依诺洛酮和溶菌酶是一种新型药物，同时对解决病毒性咽喉炎或细菌性咽喉炎疼痛是安全的。双氯虫酚可单独使用，也可与其他药物联合使用。在分析数据中，双氯虫酚显示了其治疗效果和安全性。因此，推荐以双小叶酯为基础的产品用于急性病毒性和细菌性咽炎或扁桃体炎，无论是单组分药物还是固定剂量组合，都是安全的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Otorhinolaryngology Clinics Medicine-Otorhinolaryngology

CiteScore

0.10

自引率

0.00%

发文量

期刊介绍： Otorhinolaryngology Clinics: An International Journal is an International periodical devoted at exploring connections between clinical experience and world literature, and understanding of various pathologies and diseases related to the ear, nose and throat. Issues of recent advancements and research related to disease, illness, health and medical science are examined through various evidence-based clinical research studies. This journal proposes to serve as a collection of clinical notes, with an international perspective, along with the recent advances for postgraduates and consultants. The readership for this journal would include a wide variety of healthcare professionals, such as otolaryngologists, head and neck surgeons, ENT nurses as well as scholars and academicians in the field of medicine, trauma, surgery, etc. This journal aims to encourage the analysis of clinical data from various centers all over the world using standardized protocols to develop an international consensual perspective on the management of disorders related to the field of otorhinolaryngology. Recently, we have introduced "Case Reports", "How I Do It" and "Original Research" categories in the process of expanding the scope of the journal. Thisis a peer-reviewed journal of which three issues would be published each year. Each future issue will cover a different topic of special interest in the field of otorhinolaryngology and head and neck surgery. This issue is the first of its kind dedicated to "anesthesia in otorhinolaryngology" and contains a compilation of articles by experienced anesthesiologists dealing with a large volume of ENT and related surgeries. In each issue, the editors give their perspective based on the submitted articles. All non invited articles are peer-reviewed. Peer-revieweing helps in providing unbiased, independent, critical assessment of the results of the research study in question including the scientific process.