Serum Protein Electrophoretic in Children.

IF 1.3 Q3 PEDIATRICS
Safaa Hadrach, Imane Benazzouz
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引用次数: 0

Abstract

Serum protein electrophoresis is a simple, reliable, and specific method used for separation of serum proteins. This study consisted to detect, at pediatric cases, pathological profiles of serum proteins by capillary electrophoresis and interpret any anomalies. The study was performed on 81 sera collected from pediatric subjects admitted at the Abderrahim Harouchi Children's Hospital in Casablanca. Study results revealed 72 specific pathological electrophoretic patterns for acute and chronic inflammatory response (35 children), hypogammaglobulinemia (3), polyclonal hypergammaglobulinemia (23), hypoalbuminemia (5), agammaglobulinemia (1), and other medical conditions (2). No cases of alpha-1-antitrypsin deficiency and nephrotic syndrome by electrophoresis were highlighted. Serum protein electrophoresis in children is recommended as a diagnostic technique for increasing the accuracy of the diagnosis in acute, subacute, and chronic inflammatory diseases, liver disease, and cases of immunodeficiency.

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儿童血清蛋白电泳。
血清蛋白电泳是一种简单、可靠、特异的血清蛋白分离方法。本研究包括通过毛细管电泳检测儿童病例的血清蛋白病理特征并解释任何异常。这项研究是在卡萨布兰卡的Abderrahim Harouchi儿童医院收集的81份儿科受试者的血清中进行的。研究结果揭示了急性和慢性炎症反应(35例儿童)、低γ球蛋白血症(3例)、多克隆高γ球蛋白血症(23例)、低白蛋白血症(5例)、无γ球蛋白血症(1例)和其他医学病症(2例)的72种特定病理电泳模式。电泳未显示α -1-抗胰蛋白酶缺乏症和肾病综合征。儿童血清蛋白电泳被推荐作为一种诊断技术,用于提高急性、亚急性和慢性炎症性疾病、肝脏疾病和免疫缺陷病例的诊断准确性。
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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
审稿时长
4 weeks
期刊介绍: International Journal of Pediatrics is a peer-reviewed, open access journal that publishes original researcharticles, review articles, and clinical studies in all areas of pediatric research. The journal accepts submissions presented as an original article, short communication, case report, review article, systematic review, or letter to the editor.
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