Cardiac cachexia: the mandate to increase clinician awareness.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
A. Lena, N. Ebner, A. Coats, M. Anker
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引用次数: 11

Abstract

PURPOSE OF REVIEW Heart failure is a frequent problem in an ageing population, associated with high rates of morbidity and mortality. Today, it is important to not only treat heart failure itself but also the related comorbidities. Among them, cardiac cachexia is one of the major challenges. It is a complex multifactorial disease with a negative impact on quality of life and prognosis. Therefore, prevention, early recognition and treatment of cardiac cachexia is essential. RECENT FINDINGS Cardiac cachexia frequently presents with skeletal as well as heart muscle depletion. Imaging-based diagnostic techniques can help to identify patients with cardiac cachexia and muscle wasting. Several blood biomarkers are available to detect metabolic changes in cardiac cachexia. SUMMARY Several studies are currently ongoing to better comprehend the underlying pathophysiological mechanisms of cardiac cachexia and to find new treatments. It is essential to diagnose it as early as possible to initiate therapy.
心脏恶病质:提高临床医生意识的任务。
心力衰竭是老龄化人口中的一个常见问题,与高发病率和死亡率相关。今天,重要的是不仅要治疗心力衰竭本身,还要治疗相关的合并症。其中,心脏恶病质是主要挑战之一。它是一种复杂的多因素疾病,对生活质量和预后有负面影响。因此,预防、早期识别和治疗心脏恶病质至关重要。心脏恶病质经常表现为骨骼和心肌耗竭。基于影像的诊断技术可以帮助识别心脏恶病质和肌肉萎缩的患者。几种血液生物标志物可用于检测心脏恶病质的代谢变化。目前正在进行一些研究,以更好地了解心脏恶病质的潜在病理生理机制,并寻找新的治疗方法。尽早诊断并开始治疗是至关重要的。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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