Infectious Disease Spreading Fought by Multiple Vaccines Having a Prescribed Time Effect

IF 1.4 4区 生物学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Rinaldo M. Colombo, Mauro Garavello
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引用次数: 2

Abstract

We propose a framework for the description of the effects of vaccinations on the spreading of an epidemic disease. Different vaccines can be dosed, each providing different immunization times and immunization levels. Differences due to individuals’ ages are accounted for through the introduction of either a continuous age structure or a discrete set of age classes. Extensions to gender differences or to distinguish fragile individuals can also be considered. Within this setting, vaccination strategies can be simulated, tested and compared, as is explicitly described through numerical integrations.

Abstract Image

具有规定时间效应的多种疫苗对抗传染病传播
我们提出了一个描述疫苗接种对流行病传播影响的框架。可以使用不同的疫苗,每种疫苗提供不同的免疫时间和免疫水平。通过引入连续的年龄结构或离散的年龄类别来解释个体年龄的差异。还可以考虑将其扩展到性别差异或区分脆弱个体。在这种情况下,疫苗接种策略可以通过数值积分进行模拟、测试和比较。
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来源期刊
Acta Biotheoretica
Acta Biotheoretica 生物-生物学
CiteScore
2.70
自引率
7.70%
发文量
19
审稿时长
3 months
期刊介绍: Acta Biotheoretica is devoted to the promotion of theoretical biology, encompassing mathematical biology and the philosophy of biology, paying special attention to the methodology of formation of biological theory. Papers on all kind of biological theories are welcome. Interesting subjects include philosophy of biology, biomathematics, computational biology, genetics, ecology and morphology. The process of theory formation can be presented in verbal or mathematical form. Moreover, purely methodological papers can be devoted to the historical origins of the philosophy underlying biological theories and concepts. Papers should contain clear statements of biological assumptions, and where applicable, a justification of their translation into mathematical form and a detailed discussion of the mathematical treatment. The connection to empirical data should be clarified. Acta Biotheoretica also welcomes critical book reviews, short comments on previous papers and short notes directing attention to interesting new theoretical ideas.
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