A Review on Aptamer-Conjugated Quantum Dot Nanosystems for Cancer Imaging and Theranostic

Abstract

Over the last 10 years, fluorescent semiconductor QD (quantum dot)-aptamer conjugates have emerged as an efficient platform for cancer imaging and therapy in animal models and in vitro. In addition, these conjugates show potential in a wide range of applications in environmental monitoring, disease diagnosis, and bio-sensing. The present review represents the recent developments in QDaptamer bio-conjugates for applications in cancer studies. It starts with a brief introduction to Semiconductor Quantum dots (QDs), bio-conjugation of QDs and aptamer molecules, and advantages-disadvantages of using these novel tools for biochemical applications.