Is There a Relationship Between the Severity of Preeclampsia and Fetal Renal Doppler Indices?

IF 0.8 Q4 REPRODUCTIVE BIOLOGY
Elnaz Afsari, F. Abbasalizadeh, Z. Fardiazar, Saeedeh Shahali, Y. Ahmadi
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引用次数: 1

Abstract

Objectives: Preeclampsia is a high prevalence complication in pregnancy and is responsible for 36% of maternal mortality worldwide. The offspring of mothers with preeclampsia face many problems after birth and in their lifetime. The fetal renal is one of the most vulnerable organs following maternal preeclampsia. In this regard, the present study investigated the relationship between the severity of preeclampsia and fetal renal artery resistance and pulsatility. Materials and Methods: In general, 91 pregnant women were included and divided into control and preeclampsia groups. The control group included 43 women with normal pregnancy and the preeclampsia group consisted of 48 pregnant women who suffered from preeclampsia and were classified into patients in severe and non-severe preeclampsia groups each containing 24 cases. Renal artery Doppler ultrasound was performed, and then the systole/diastole ratio (S/D), pulsatility index (PI), and resistance index (RI) were measured as well. Results: The S/D ratio, RI, and PI significantly decreased in the preeclampsia group (P<0.001) compared to the control group. The S/D ratio in severe preeclampsia was significantly lower in comparison with non-severe preeclampsia (P<0.001). Finally, the amniotic fluid index was related to the PI (P<0.05), and severe preeclampsia significantly increased the pregnancy termination before 34 weeks (P<0.001). Conclusions: Preeclampsia deceased the resistance of renal arteries by altering the fetal renal blood flow. These changes can intensify in patients with severe preeclampsia compared to non-severe preeclampsia.
子痫前期严重程度与胎儿肾多普勒指数有关系吗?
目的:先兆子痫是一种高患病率的妊娠并发症,占全球孕产妇死亡率的36%。子痫前期母亲的后代在出生后和一生中面临许多问题。胎儿肾脏是母体子痫前期最脆弱的器官之一。在这方面,本研究探讨子痫前期严重程度与胎儿肾动脉阻力和搏动的关系。材料与方法:共纳入91例孕妇,分为对照组和子痫前期组。对照组为43例正常妊娠妇女,子痫前期组为48例发生子痫前期的孕妇,分为重度子痫前期组和非重度子痫前期组,每组24例。行肾动脉多普勒超声检查,测定肾动脉收缩期/舒张期比值(S/D)、脉搏指数(PI)、阻力指数(RI)。结果:子痫前期组S/D比、RI、PI较对照组显著降低(P<0.001)。重度子痫前期患者的S/D比显著低于非重度子痫前期患者(P<0.001)。羊水指数与PI相关(P<0.05),重度子痫前期显著增加34周前终止妊娠(P<0.001)。结论:子痫前期通过改变胎儿肾血流量来降低肾动脉的阻力。与非重度子痫前期患者相比,重度子痫前期患者的这些变化可能会加剧。
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来源期刊
CiteScore
1.60
自引率
14.30%
发文量
8
期刊介绍: All kind of knowledge contributing to the development of science by its content, value, level and originality will be covered by IJWHR. Problems of public health and their solutions are at the head of the windows opening us to the world. The "International Journal of Women''s Health and Reproduction Sciences” is a modern forum for scientific communication, covering all aspects women health and reproduction sciences, in basic and clinical sciences, mainly including: -Medical Education in Women Health and Reproduction Sciences -Cardiology in Women Health-Related Reproductive Problems -Sports Medicine in Women Health and Reproduction Sciences -Psychiatry in Women Health-Related Reproductive Problems -Antioxidant Therapy in Reproduction Medicine Sciences -Nutrition in Women Health and Reproduction Sciences -Defense Androgen and Estrogen -Fertility and Infertility -Urogynecology -Endometriosis -Endocrinology -Breast Cancer -Menopause -Puberty -Eroticism -Pregnancy -Preterm Birth -Vaginal Diseases -Sex-Based Biology -Surgical Procedures -Nursing in Pregnancy -Obstetrics/Gynecology -Polycystic Ovary Syndrome -Hyperandrogenism in Females -Menstrual Syndrome and Complications -Oncology of Female Reproductive Organs -Traditional Medicine in Women Reproductive Health -Ultrasound in Women Health Reproduction sciences -Stem Cell Research In Women Reproduction Sciences -Complementary Medicine in Women Reproductive Health -Female Sexual Dysfunction: Pathophysiology & Treatment
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