Serum markers of cardiac dysfunction in patients with carbohydrate metabolism disorder during post-infraction rehabilitation

Abstract

The article is devoted to the study of the diagnostic informative value of serum cardiac markers (troponin I, caspase-8, amphiphysin-2) in patients with impaired carbohydrate metabolism after myocardial infarction. The study conducted on the 10th day of the post-infarction period showed no relationship between the types of myocardial infarction and the severity of carbohydrate metabolism disorders. The study revealed an increase in amphiphysin-2 in patients of the study group compared with the control group, while the sensitivity and specificity of amphiphysin-2 in patients with Q-MI and non-Q MI were 97.8 and 13.0%, respectively. Elevated levels of amphiphysin-2 were accompanied by a simultaneous increase in serum levels of caspase-8 in the group of patients with myocardial infarction.