NMR and molecular dynamics studies combined to anti–cancer nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations
{"title":"NMR and molecular dynamics studies combined to anti–cancer nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000368","DOIUrl":null,"url":null,"abstract":"In the current research, NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations are considered. The early diagnosis of cancer is very important for patient treatment and recovery. If cancers can be confirmed and classified at an early stage, the patient survival rate can be greatly improved. Current clinical cancer diagnostic techniques can be divided into two catalogs: tissue imaging and NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations. *Correspondence to: Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604; American International Standards Institute, Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmail. com; Alireza.Heidari@calsu.us; Central@aisi-usa.org","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dental, Oral and Maxillofacial Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/DOMR.1000368","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 13
Abstract
In the current research, NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations are considered. The early diagnosis of cancer is very important for patient treatment and recovery. If cancers can be confirmed and classified at an early stage, the patient survival rate can be greatly improved. Current clinical cancer diagnostic techniques can be divided into two catalogs: tissue imaging and NMR and molecular dynamics studies combined to anti–cancer Nano drugs and DNA/RNA interactions in gum cancer cells and their modulations with resistance mutations. *Correspondence to: Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604; American International Standards Institute, Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmail. com; Alireza.Heidari@calsu.us; Central@aisi-usa.org
在目前的研究中,考虑了核磁共振和分子动力学结合抗癌纳米药物和DNA/RNA在牙龈癌细胞中的相互作用及其对耐药突变的调节。癌症的早期诊断对患者的治疗和康复非常重要。如果癌症能够在早期得到确认和分类,患者的存活率可以大大提高。目前的临床癌症诊断技术可分为两大类:组织成像和核磁共振以及结合抗癌纳米药物和牙龈癌细胞中DNA/RNA相互作用及其对耐药突变的调节的分子动力学研究。*通讯:Alireza Heidari,南加州大学化学系,14731 Comet St. Irvine, CA 92604;美国国际标准协会,Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmailcom;Alireza.Heidari@calsu.us;Central@aisi-usa.org