Fibrolamellar Hepatocellular Carcinoma: Report of a Rare Case with Rapid Progression and Unusual Metastatic Sites

Abstract

Fibrolamellar hepatocellular carcinoma (FLHCC) is a rare primary liver cancer that occurs in young adults, and its biology is not well known. We present a 21-year-old woman with metastatic liver cancer 6 months after undergoing embolization procedures for a typical hemangioma. The pathological investigation confirmed metastatic FLHCC. Despite liver mass resection and lung metastasectomy, after 3 months, the tumor recurred. In 18F-FDG PET-CT scan, lung, ovary, colon, and peritoneal invasions were reported. Unfortunately, the patient died a year after diagnosis due to a rapid progression and multiple unusual metastatic sites.