Biomarkers in acute coronary syndrome

David del Val Martin, Marcelo Sanmartín Fernández, Jose Luís Zamorano Gómez
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引用次数: 9

Abstract

Background

Biomarkers play an important role in the diagnosis and risk stratification of patients with ischemic heart disease. Currently, troponin continues as the reference biomarker in acute coronary syndromes. However, there are other biomarkers that have shown additional value in improving sensitivity and prognostic information. Several promising molecules are reviewed, some related to cardiomyocyte structure and others working as inflammatory and renal function markers.

Conclusions

Although many biomarkers have been shown useful in some studies, further prospective studies are needed to establish their accurate usefulness in routine clinical practice.

急性冠状动脉综合征的生物标志物
生物标志物在缺血性心脏病患者的诊断和危险分层中起着重要作用。目前,肌钙蛋白继续作为急性冠脉综合征的参考生物标志物。然而,还有其他生物标志物在提高敏感性和预后信息方面显示出额外的价值。综述了几种有前途的分子,一些与心肌细胞结构有关,另一些作为炎症和肾功能标志物。结论尽管许多生物标志物在一些研究中显示出有用,但需要进一步的前瞻性研究来确定它们在常规临床实践中的准确用途。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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