Lifestyle medicine – An evidence based approach to nutrition, sleep, physical activity, and stress management on health and chronic illness

Personalized Medicine Universe Pub Date : 2019-07-01 DOI:10.1016/j.pmu.2019.05.002

Minako Abe , Hiroyuki Abe

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引用次数: 18

Abstract

Lifestyle-related chronic illnesses, such as metabolic syndrome, type 2 diabetes, cancer, and dementia are rising at an alarming, epidemic rate. In this modern world of increasing lifespan, we are actually decreasing our health span, placing an undue burden on healthcare costs to society. Modern medicine has largely gotten away from addressing key issues to prevent or even reverse some of these chronic conditions. Yet the evidence for successful interventions in four key areas – nutrition, sleep, physical activity and stress management – to manage and control our health are mounting. Lifestyle medicine as a part of personalized treatment and prevention of chronic illnesses is a necessary cornerstone of disease management as we look to the future. In this review, I discuss various key studies demonstrating the impact of lifestyle on epigenetic, endocrine, immunologic, and inflammatory changes which contribute to chronic disease and our overall health.

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生活方式医学-以证据为基础的营养，睡眠，身体活动，健康和慢性疾病的压力管理方法

与生活方式有关的慢性疾病，如代谢综合征、2型糖尿病、癌症和痴呆症，正在以惊人的流行病速度上升。在这个寿命延长的现代世界里，我们实际上是在缩短我们的健康寿命，给社会带来了不必要的医疗费用负担。现代医学在很大程度上没有解决预防甚至逆转这些慢性疾病的关键问题。然而，越来越多的证据表明，在营养、睡眠、体育活动和压力管理这四个关键领域，成功的干预措施可以管理和控制我们的健康。生活方式医学作为慢性病个性化治疗和预防的一部分，是我们展望未来时疾病管理的必要基石。在这篇综述中，我讨论了各种证明生活方式对表观遗传、内分泌、免疫和炎症变化的影响的关键研究，这些变化有助于慢性疾病和我们的整体健康。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Personalized Medicine Universe

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